Do intra-operative fluids influence the need for Post-operative cardiotropic support after a PDA ligation?

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Abstract OBJECTIVE: To investigate the effect of intra-operative intravenous fluids on post-operative hemodynamic stability. METHODS: We performed a retrospective cohort study of 98 preterm infants who underwent a patent ductus arteriosus (PDA) ligation in one NICU between 2001 and 2007. The primary outcome was the need for cardiotropic support within 24 hrs of ligation. RESULTS: Twenty-seven infants (28%) required post-operative cardiotropic support. The amount of intra-operative fluids varied between 0 and 50.4 mL/kg (median: 10.2 mL/kg). No intra-operative fluid was recorded in 26 patients. Fluids were not associated with the need for post-operative cardiotropic support (P=0.10). Using a multivariate logistic regression model, age at ligation, weight at ligation and pre-operative FiO2 were significant predictors of post-operative cardiotropic support. CONCLUSIONS: Intra-operative fluids do not appear to be associated with the need for post-operative cardiotropic support. A prospective cohort study may help identify modifiable risk factors and improve outcomes in this population.

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	Articles by authors
	Brigitte LEMYRE
	Ling LIU
	Gregory Paul MOORE
	Sarah Linda LAWRENCE
	Nicholas J. BARROWMAN

Key words： Hemodynamics Patent ductus arteriosus ligation Premature infant

PACS:

R541.1

Cite this article:

Brigitte LEMYRE,Ling LIU,Gregory Paul MOORE et al. Do intra-operative fluids influence the need for Post-operative cardiotropic support after a PDA ligation?[J]. 中国当代儿科杂志, 2011, 13(1): 1-7.

Brigitte LEMYRE,Ling LIU,Gregory Paul MOORE et al. Do intra-operative fluids influence the need for Post-operative cardiotropic support after a PDA ligation?[J]. CJCP, 2011, 13(1): 1-7.

URL:

http://www.zgddek.com/EN/ OR http://www.zgddek.com/EN/Y2011/V13/I1/1

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