Abstract OBJECTIVE: To study the progression of myopia in school-age children over the past 12 years and factors influencing myopia progression. METHODS: A total of 4569 cases of 5 to 12-year-old children who had refractive examinations in the Third Xiangya Hospital, Central South University between January 2000 and December 2011 were enrolled in this study. The children had no family history of congenital high myopia or other eye diseases. Myopia progression was evaluated when the children were re-examined. The refractive state of each child was measured with cyclopiegic retinoscopy. RESULTS: The mean spherical equivalent (SE) myopia was-2.0±1.7 D between January 2000 and December 2011. There was no statistical difference in yearly myopia progression between different years. The average age of the myopic children decreased from 10.1 in 2000 to 8.9 years old in 2011 (P<0.05). Mean myopia progression was -0.6±0.7 D per year from 2000 to 2011. Myopia progression reduced gradually in 5 to 8-year-olds (P<0.05), however, it accelerated between ages 9 and 11 years. Myopia progression in 10- and 11-year-olds was significantly greater than in 7- and 8-year-olds (P<0.01). The multiple linear regression analysis demonstrated that age and baseline myopic refraction were positively related to myopia progression. CONCLUSIONS: There was no obvious change in the yearly myopia progression of the children over the past 12 years. The mean age of myopia occurrence became younger with time. More preventive measures are needed to ward off high myopia in children with moderate myopia, especially those aged over 10 years.
CAO Yan-Na,TANG Reng-Hong,LI Rong-Rong et al. A retrospective study on the progression of myopia in school-age children[J]. 中国当代儿科杂志, 2012, 14(09): 693-696.
CAO Yan-Na,TANG Reng-Hong,LI Rong-Rong et al. A retrospective study on the progression of myopia in school-age children[J]. CJCP, 2012, 14(09): 693-696.
[1]Pan CW, Ramamurthy D, Saw SM. Worldwide prevalence and risk factors for myopia[J]. Ophthalmic Physiol Opt, 2012, 32(1): 3-16.
[2]Donovan L, Sankaridurg P, Ho A, Naduvilath T, Smith EL 3rd, Holden BA. Myopia progression rates in urban children wearing single-vision spectacles[J]. Optom Vis Sci, 2012, 89(1): 27-32.
[3]Vitale S, Ellwein L, Cotch MF, Ferris FL 3rd, Sperduto R. Prevalence of refractive error in the United States, 1999-2004[J]. Arch Ophthalmol, 2008, 126(8): 1111-1119.
[4]Xu L, Wang Y, Li Y, Wang Y, Cui T, Li J, et al. Causes of blindness and visual impairment in urban and rural areas in Beijing: the Beijing Eye Study[J]. Ophthalmology, 2006, 113(7): 1134.
[5]Morgan IG, Rose KA, Ellwein LB; Refractive Error Study in Children Survey Group. Is emmetropia the natural endpoint for human refractive development? An analysis of population-based data from the refractive error study in children (RESC) [J]. Acta Ophthalmol, 2011, 88(8): 877-884.
[6]Lin LL, Shih YF, Tsai CB, Chen CJ, Lee LA, Hung PT, et al. Epidemiologic study of ocular refraction among schoolchildren in Taiwan in 1995[J]. Optom Vis Sci, 1999, 76(5): 275-281.
[7]Zhao J, Mao J, Luo R, Li F, Munoz SR, Ellwein LB. The progression of refractive error in school-age children: Shunyi district, China[J]. Am J Ophthalmol, 2002, 134(5): 735-743.
[8]Saw SM, Tong L, Chua WH, Chia KS, Koh D, Tan DT, et al. Incidence and progression of myopia in Singaporean school children[J]. Invest Ophthalmol Vis Sci, 2005, 46(1): 51-57.
[10]Pi LH, Chen L, Liu Q, Ke N, Fang J, Zhang S, et al. Prevalence of eye diseases and causes of visual impairment in school-aged children in Western China[J]. J Epidemiol, 2012, 22(1):37-44.
[11]Lam CS, Lam CH, Cheng SC, Chan LY. Prevalence of myopia among Hong Kong Chinese schoolchildren: changes over two decades[J]. Ophthalmic Physiol Opt, 2012, 32(1): 17-24.
[12]Shih YF, Chiang TH, Hsiao CK, Chen CJ, Hung PT, Lin LL. Comparing myopic progression of urban and rural Taiwanese schoolchildren[J]. Jpn J Ophthalmol, 2010, 54(5): 446-451.
[13]Saw SM, Chua WH, Gazzard G, Koh D, Tan DT, Stone RA. Eye growth changes in myopic children in Singapore[J]. Br J Ophthalmol, 2005, 89(11): 1489-1494.
[15]Zhao J, Pan X, Sui R, Munoz SR, Sperduto RD, Ellwein LB. Refractive Error Study in Children: results from Shunyi District, China[J]. Am J Ophthalmol, 2000, 129(4): 427-435.
[16]Stone RA, Khurana TS. Gene profiling in experimental models of eye growth: clues to myopia pathogenesis[J]. Vision Res, 2010, 50(23): 2322-2333.
[17]Tabernero J, Ohlendorf A, Fischer MD, Bruckmann AR, Schiefer U, Schaeffel F. Peripheral refraction profiles in subjects with low foveal refractive errors[J]. Optom Vis Sci, 2011, 88(3): E388-394.
[18]Ehsaei A, Mallen EA, Chisholm CM, Pacey IE. Cross-sectional sample of peripheral refraction in four meridians in myopes and emmetropes[J]. Invest Ophthalmol Vis Sci, 2011, 52(10): 7574-7585.