Abstract Objective To study the clinical features and risk factors of co-morbid tic disorder（TD) in children with attention deficit hyperactivity disorder（ADHD). Methods A total of 312 children with ADHD were involved in this study. Subtypes of co-morbid TD, incidences of TD in different subtypes of ADHD（ADHD-I, ADHD-HI and ADHD-C) were observed. Thirteen potential factors influencing the comorbidity rate of TD in ADHD were evaluated by univariate analysis and multiple logistic regression analysis. Results Forty-two of 312 children with ADHD suffered from co-morbid TD（13.5%). Comorbidity rate of TD in children with ADHD-C（24.1%) was significantly higher than in those with ADHD-HI（10.9%) and ADHD-I（8.8%)（POR=7.000, POR=2.564,PConclusion The incidence of co-morbid TD in children with ADHD is influenced by many factors, and early interventions should be performed based on the main risk factors.
ZHOU Ke-Ying,XIAO Zhi-Hui,CHEN Yan-Zhao et al. Clinical features and risk factors of co-morbid tic disorder in children with attention deficit hyperactivity disorder[J]. CJCP, 2014, 16(9): 892-895.
ZHOU Ke-Ying,XIAO Zhi-Hui,CHEN Yan-Zhao et al. Clinical features and risk factors of co-morbid tic disorder in children with attention deficit hyperactivity disorder[J]. CJCP, 2014, 16(9): 892-895.
American Psychiatric Association.Diagnostic and Statistical Manual of Mental Disorders[M].4th ed Text Revision（DSM-IVTR).Washington, DC: American Psychiatric Association,2000.
Daniela LK, Norbert M.The relationship between Tourette's syndrome and infections[J].Open Neurol J, 2012, 6(Suppl 1-M8): 124-128.
[11]
Martino D, Chiarotti F, Buttiglione M, et al.The relationship between group A streptococcal infections and Tourette syndrome: a study on a large service-based cohort[J].Dev Med Child Neurol, 2011, 53(10): 951-957.
