Clinical features and risk factors of co-morbid tic disorder in children with attention deficit hyperactivity disorder

ZHOU Ke-Ying, XIAO Zhi-Hui, CHEN Yan-Zhao, ZHANG Zhao-Xia, LIU Zhi-Ping, YANG Chun-He, GAO Mei-Hao

Chinese Journal of Contemporary Pediatrics ›› 2014, Vol. 16 ›› Issue (9) : 892-895.

PDF(1133 KB)
PDF(1133 KB)
Chinese Journal of Contemporary Pediatrics ›› 2014, Vol. 16 ›› Issue (9) : 892-895. DOI: 10.7499/j.issn.1008-8830.2014.09.005
CLINICAL RESEARCH

Clinical features and risk factors of co-morbid tic disorder in children with attention deficit hyperactivity disorder

  • ZHOU Ke-Ying1, XIAO Zhi-Hui1, CHEN Yan-Zhao1, ZHANG Zhao-Xia1, LIU Zhi-Ping1, YANG Chun-He1, GAO Mei-Hao2
Author information +
History +

Abstract

Objective To study the clinical features and risk factors of co-morbid tic disorder(TD) in children with attention deficit hyperactivity disorder(ADHD). Methods A total of 312 children with ADHD were involved in this study. Subtypes of co-morbid TD, incidences of TD in different subtypes of ADHD(ADHD-I, ADHD-HI and ADHD-C) were observed. Thirteen potential factors influencing the comorbidity rate of TD in ADHD were evaluated by univariate analysis and multiple logistic regression analysis. Results Forty-two of 312 children with ADHD suffered from co-morbid TD(13.5%). Comorbidity rate of TD in children with ADHD-C(24.1%) was significantly higher than in those with ADHD-HI(10.9%) and ADHD-I(8.8%)(P<0.05). There were 21 cases(50.0%) of transient TD, 12 cases(28.6%) of chronic TD, and 9 cases(21.4%) of Tourette syndrome. The univariate analysis revealed 6 factors associated with comorbidity: addiction to mobile phone or computer games, poor eating habits, infection, improper family education, poor relationship between parents and poor relationship with schoolmates. Multiple logistic analysis revealed two independent risk factors for comorbidity: improper family education(OR=7.000, P<0.05) and infection(OR=2.564,P<0.05). Conclusion The incidence of co-morbid TD in children with ADHD is influenced by many factors, and early interventions should be performed based on the main risk factors.

Key words

Attention deficit hyperactivity disorder / Tic disorder / Clinical feature / Risk factor / Child

Cite this article

Download Citations
ZHOU Ke-Ying, XIAO Zhi-Hui, CHEN Yan-Zhao, ZHANG Zhao-Xia, LIU Zhi-Ping, YANG Chun-He, GAO Mei-Hao. Clinical features and risk factors of co-morbid tic disorder in children with attention deficit hyperactivity disorder[J]. Chinese Journal of Contemporary Pediatrics. 2014, 16(9): 892-895 https://doi.org/10.7499/j.issn.1008-8830.2014.09.005

References

[1] Taurines R, Schmitt J, Renner T, et al.Developmental comorbidity in attention-deficit/hyperactivity disorder[J].Atten Defic Hyperact Disord, 2010, 2(4): 267-289.
[2] 周克英, 高美好, 杨春何, 等.深圳市小学儿童注意缺陷多动障碍流行病学调查 [J].中国当代儿科杂志, 2012, 14(9):689-692.
[3] 肖朝华, 王庆红, 罗甜甜, 等.儿童注意缺陷多动障碍共患病及功能损害研究 [J].中国当代儿科杂志, 2013, 15(9): 728-732.
[4] 静进.儿童注意缺陷多动障碍诊疗进展 [J].实用儿科临床杂志, 2012, 27(12): 965-970.
[5] American Psychiatric Association.Diagnostic and Statistical Manual of Mental Disorders[M].4th ed Text Revision(DSM-IVTR).Washington, DC: American Psychiatric Association,2000.
[6] 陈言钊, 文飞球, 周克英, 等.不同亚型注意缺陷多动障碍患儿的临床特征分析 [J].中国当代儿科杂志, 2010, 12(9):704-708.
[7] 雷爽, 韩新民.注意力缺陷多动障碍与多巴胺、去甲肾上腺素关系的研究进展 [J].中国儿童保健杂志, 2013, 21(9): 953-955.
[8] 齐越, 魏小维.多发性抽动症发病相关因素的研究进展 [J].中国儿童保健杂志, 2013, 21(6): 618-619.
[9] 陈江鱼, 赵宏伊, 李杰, 等.儿童抽动障碍与病原微生物感染及其免疫的相关性 [J].实用儿科临床杂志, 2012, 27(19):1536-1537.
[10] Daniela LK, Norbert M.The relationship between Tourette's syndrome and infections[J].Open Neurol J, 2012, 6(Suppl 1-M8): 124-128.
[11] Martino D, Chiarotti F, Buttiglione M, et al.The relationship between group A streptococcal infections and Tourette syndrome: a study on a large service-based cohort[J].Dev Med Child Neurol, 2011, 53(10): 951-957.
[12] 夏经.多发性抽动症的病因与发病机制 [J].中国实用儿科杂志, 2002, l7(4): 199.
[13] 吴舒华, 刘智胜,孙丹,等.Tourette 综合征患儿的预后及影响因素 [J].实用儿科临床杂志, 2008, 23(12): 934-935.
[14] 徐通, 周翊.儿童抽动障碍病因及发病机制 [J].实用儿科临床杂志, 2012, 27(7): 502-505.
PDF(1133 KB)

Accesses

Citation

Detail

Sections
Recommended

/