Etiology and diagnosis of intellectual disability

YANG Pu; GUI Bao-Heng; WU Ling-Qian

doi:10.7499/j.issn.1008-8830.2015.06.002

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Chinese Journal of Contemporary Pediatrics ›› 2015, Vol. 17 ›› Issue (6) : 543-548. DOI: 10.7499/j.issn.1008-8830.2015.06.002

TOPIC OF NERVOUS SYSTEM DISEASE

Etiology and diagnosis of intellectual disability

YANG Pu, GUI Bao-Heng, WU Ling-Qian

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Abstract

Intellectual disability, occurring in 1%-3% of the general population, is a common disease of the nervous system in children. Since diverse genetic and environmental factors contribute to its pathogenesis, the etiological diagnosis of intellectual disability is challenging with respect to the selection of diagnostic tests. It is important to determine the etiology of intellectual disability for the assessment of prognosis, treatment and the family plan. This paper summarizes the research progress in etiology and diagnosis for intellectual disability and introduces the recommended clinical genetics diagnostic approach from the American Academy of Pediatrics.

Key words

Intellectual disability / Etiology / Diagnosis / Child

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YANG Pu, GUI Bao-Heng, WU Ling-Qian. Etiology and diagnosis of intellectual disability[J]. Chinese Journal of Contemporary Pediatrics. 2015, 17(6): 543-548 https://doi.org/10.7499/j.issn.1008-8830.2015.06.002

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