Asymmetric crying facies and vocal cord paralysis accompanied by congenital heart disease in an infant

WEI Hong-Ling; PIAO Mei-Hua; ZHANG Juan; LIU Ling; CHANG Yan-Mei

doi:10.7499/j.issn.1008-8830.2019.06.016

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Chinese Journal of Contemporary Pediatrics ›› 2019, Vol. 21 ›› Issue (6) : 585-588. DOI: 10.7499/j.issn.1008-8830.2019.06.016

CASE ANALYSIS

Asymmetric crying facies and vocal cord paralysis accompanied by congenital heart disease in an infant

WEI Hong-Ling, PIAO Mei-Hua, ZHANG Juan, LIU Ling, CHANG Yan-Mei

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Abstract

A female infant was admitted to the hospital due to perioral cyanosis two hours after birth. The infant was born at the gestational age of 35 weeks by cesarean section with a birth weight of 2 400 g. Physical examination revealed wry mouth to the left side while crying, small auricles, and high palatal arch; fibrolaryngoscopy suggested bilateral vocal cord paralysis; echocardiography suggested ventricular septal defect; single nucleotide polymorphism testing showed 22q11.21 microdeletion. Therefore, the infant was given a definite diagnosis of asymmetric crying facies syndrome accompanied by 22q11.21 microdeletion. After 8-month follow-up, the infant still had asymmetric crying facies with presence of growth retardation.

Key words

Asymmetric crying facies / Vocal cord paralysis / 22q11.21 microdeletion / Infant

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WEI Hong-Ling, PIAO Mei-Hua, ZHANG Juan, LIU Ling, CHANG Yan-Mei. Asymmetric crying facies and vocal cord paralysis accompanied by congenital heart disease in an infant[J]. Chinese Journal of Contemporary Pediatrics. 2019, 21(6): 585-588 https://doi.org/10.7499/j.issn.1008-8830.2019.06.016

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