Short-term prognosis of the co-twin who survives after single intrauterine fetal demise

WANG Lian; LIN Xin-Zhu

doi:10.7499/j.issn.1008-8830.2019.09.008

PDF(1167 KB)

Chinese Journal of Contemporary Pediatrics ›› 2019, Vol. 21 ›› Issue (9) : 886-889. DOI: 10.7499/j.issn.1008-8830.2019.09.008

CLINICAL RESEARCH

Short-term prognosis of the co-twin who survives after single intrauterine fetal demise

WANG Lian, LIN Xin-Zhu

Author information +

History +

Abstract

Objective To investigate the short-term prognosis of the co-twin who survives after single intrauterine fetal demise (sIUFD). Methods A total of 52 infants who survived after sIUFD were enrolled as the case group, and 104 twins, matched for gestational age, from a pair of live-born twins without sIUFD were enrolled as the control group. Related clinical data were compared between the two groups. Results Among the 52 infants who survived after sIUFD, 42 (80.8%) were preterm infants, 13 (25.0%) had brain injury, and 3 (5.8%) died in the neonatal period. Compared with the control group, the case group had significantly higher incidence rates of meconium stained amniotic fluid/bloody amniotic fluid/polyhydramnios/hypamnion, torsion of cord/nuchal cord, and placenta previa/placenta abruption, as well as significantly higher incidence rates of birth asphyxia, anemia or polycythemia at birth, and coagulation disorder at birth (P < 0.05). The case group also had significantly higher incidence rates of nosocomial infection and brain injury than the control group during hospitalization (P < 0.05). Conclusions There is an increase in the incidence rate of complications in the co-twin who survives after sIUFD. Prenatal evaluation and long-term follow-up should be performed for the surviving co-twin.

Key words

Twin pregnancy / Intrauterine fetal demise / Complication / Prognosis / Neonate

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

WANG Lian, LIN Xin-Zhu. Short-term prognosis of the co-twin who survives after single intrauterine fetal demise[J]. Chinese Journal of Contemporary Pediatrics. 2019, 21(9): 886-889 https://doi.org/10.7499/j.issn.1008-8830.2019.09.008

References

[1] Odibo AO. Single intrauterine fetal death in twin pregnancies is associated with increased risk of preterm birth and abnormal antenatal brain imaging in the surviving co-twin[J]. BJOG, 2019, 126(5):579.
[2] 王颖, 魏瑗, 原鹏波, 等. 单绒毛膜双胎之一胎死宫内的共存儿预后分析[J]. 中华医学杂志, 2016, 96(37):3003-3007.
[3] 宋晶, 陈奕. 37例双胎一胎胎死宫内后存活儿预后分析[J]. 实用妇产科杂志, 2018, 34(1):46-49.
[4] 郭永建, 马春会. 英国小儿输血指南主要推荐及其启示(续1)[J].中国输血杂志, 2017, 30(11):1312-1320.
[5] 刘敬, 杨于嘉, 封志纯. "早产儿脑损伤诊断与防治专家共识"解读[J]. 中国当代儿科杂志, 2012, 14(12):885-887.
[6] Almog B, Levin I, Wagman I, et al. Adverse obstetric outcome for the vanishing twin syndrome[J]. Reprod Biomed Online, 2010, 20(2):256-260.
[7] 许碧秋, 唐婉颖, 蒋小萃, 等.影响双胎之一胎死宫内母儿预后的相关因素分析[J]. 中国实用医药, 2016, 11(30):286-287.
[8] Vale-Fernandes E, Dias J, Gil B, et al. Single fetal death in monochorionic twin pregnancy:co-twin prognosis and neonatal outcome[J]. Acta Med Port, 2017, 30(2):148-151.
[9] 郑文佩, 张志涛, 庄艳艳, 等. 2013年全国多中心双胎胎膜早破临床分析[J]. 中国实用妇科与产科杂志, 2017, 33(2):67-70.
[10] 李思慧, 龚景进, 莫金桦, 等. 单、双胎早产的高危因素及早产儿结局比较研究[J]. 中国实用妇科与产科杂志, 2018, 34(2):171-175.
[11] Mackie FL, Rigby A, Morris RK, et al. Prognosis of the co-twin following spontaneous single intrauterine fetal death in twin pregnancies:a systematic review and meta-analysis[J]. BJOG, 2019, 126(5):569-578.
[12] Giwnewer U, Wiznitzer A, Friedler JM, et al. Intrauterine fetal death of one twin of diamnionic twins is associated with adverse perinatal outcome of the co-twin[J]. J Matern Fetal Neonatal Med, 2012, 25(8):1453-1455.
[13] Takita H, Hasegawa J, Nakamura M, et al. Causes of intrauterine fetal death are changing in recent years[J]. J Perinat Med, 2018, 46(1):97-101.
[14] Persico N, D'Ambrosi F, Fabietti I, et al. Fetal Doppler changes 1 week after endoscopic equatorial laser for twin-to-twin transfusion syndrome:a longitudinal study[J]. Prenat Diagn, 2018, 38(5):344-348.
[15] 葛均泼, 徐永健. 内科学[M]. 第8版. 北京:人民卫生出版社, 2013:634-638.
[16] 王学举, 魏瑗. 双胎之一胎死宫内孕晚期发生亚急性弥散性血管内凝血1例报道[J]. 中国产前诊断杂志(电子版), 2015, 7(3):58-60.
[17] 谯小勇, 曹曦, 刑爱耘. 双胎妊娠一胎宫内死亡34例临床分析[J]. 实用妇产科杂志, 2011, 27(2):138-141.
[18] Mackie FL, Morris RK, Kilby MD. Fetal brain injury in survivors of twin pregnancies complicated by demise of one twin:a review[J]. Twin Res Hum Genet, 2016, 19(3):262-267.
[19] Hillman SC, Morris RK, Kilby MD. Co-twin prognosis after single fetal death:a systematic review and meta-analysis[J]. Obstetr Gynecol, 2011, 118(4):928-940.
[20] van Klink JM, van Steenis A, Steggerda SJ, et al. Single fetal demise in monochorionic pregnancies:incidence and patterns of cerebral injury[J]. Ultrasound Obstet Gynecol, 2015, 45(3):294-300.
[21] 刘秀娟, 魏瑗, 赵扬玉. 单绒毛膜双胎妊娠之一胎死宫内的研究进展[J]. 中华围产医学杂志, 2017, 20(4):256-259.