Abstract Objective To investigate the prevalence of diabetes mellitus (DM) among Uygur children in Hotan Prefecture of Xinjiang, China, as well as the factors influencing the development of DM. Methods The cluster random sampling method was used to select 5 308 children, aged 4-18 years, from the middle and primary schools and kindergartens in Hotan Prefecture of Xinjiang. The survey methods included questionnaire survey and the measurement of height and weight. All subjects were tested for fasting fingertip blood glucose to investigate the prevalence of DM and impaired fasting glucose (IFG). Results A total of 5 184 valid questionnaires were collected. Fourteen children (0.27%) were found to have DM, among whom 8 had type 1 DM, 2 had type 2 DM, and 4 had unclassified DM. Twenty-nine children (0.56%) were found to have IFG. There was no significant difference in the prevalence rate of DM and IFG between boys and girls (P>0.05). The prevalence rate of DM was 0.18% in the 4-<10 years group, 0.47% in the 10-<15 years group, and 0.07% in the 15-18 years group (P=0.072).The prevalence rate of IFG in the above three age groups was 0.18%, 0.94%, and 0.42%, respectively, with a significant difference among groups (P=0.007). The proportion of family history of DM and the proportion of overweight/obesity in children with DM were significantly higher than those in children without DM (P<0.05), while the proportion of children with DM who preferred coarse grains was significantly lower than that in children without DM (P<0.05). Conclusions The prevalence of DM and IFG in Uyghur children in Hotan Prefecture of Xinjiang is relatively low. There is no significant difference in the prevalence of DM among children of different genders or age groups, but the prevalence of IFG in children of different age groups is different. A family history of DM, overweight or obesity, and low intake of coarse grains might be associated with the development of DM.
LUO Yan-Fei,LI Jun-Kang,MAYILA·Abudoureyimu et al. Prevalence of diabetes mellitus among Uygur children in Hotan Prefecture of Xinjiang, China[J]. CJCP, 2022, 24(2): 192-196.
LUO Yan-Fei,LI Jun-Kang,MAYILA·Abudoureyimu et al. Prevalence of diabetes mellitus among Uygur children in Hotan Prefecture of Xinjiang, China[J]. CJCP, 2022, 24(2): 192-196.
Wu HB, Zhong JM, Hu RY, et al. Rapidly rising incidence of type 1 diabetes in children and adolescents aged 0-19 years in Zhejiang, China, 2007 to 2013[J]. Diabet Med, 2016, 33(10): 1339-1346. PMID: 26499360. DOI: 10.1111/dme.13010.
Zhao ZH, Sun CJ, Wang CF, et al. Rapidly rising incidence of childhood type 1 diabetes in Chinese population: epidemiology in Shanghai during 1997-2011[J]. Acta Diabetol, 2014, 51(6): 947-953. PMID: 24777734. DOI: 10.1007/s00592-014-0590-2.
Park Y, Wintergerst KA, Zhou ZG. Clinical heterogeneity of type 1 diabetes (T1D) found in Asia[J]. Diabetes Metab Res Rev, 2017, 33(7): e2907. PMID: 28544229. DOI: 10.1002/dmrr.2907.
Wei GS, Coady SA, Goff DCJ, et al. Blood pressure and the risk of developing diabetes in African Americans and whites: ARIC, CARDIA, and the Framingham heart study[J]. Diabetes Care, 2011, 34(4): 873-879. PMID: 21346180. PMCID: PMC3064044. DOI: 10.2337/dc10-1786.
Ji CY, Chen TJ, Working Group on Obesity in China (WGOC). Empirical changes in the prevalence of overweight and obesity among Chinese students from 1985 to 2010 and corresponding preventive strategies[J]. Biomed Environ Sci, 2013, 26(1): 1-12. PMID: 23294610. DOI: 10.3967/0895-3988.2013.01.001.
18 马冠生. 中国儿童肥胖报告[M]. 北京: 人民卫生出版社, 2017.
Steyn NP, Mann J, Bennett PH, et al. Diet, nutrition and the prevention of type 2 diabetes[J]. Public Health Nutr, 2004, 7(1A): 147-165. PMID: 14972058. DOI: 10.1079/phn2003586.
Sinau S, Montaunier C, Wils D, et al. Net energy value of two low-digestible carbohydrates, Lycasin HBC and the hydrogenated polysaccharide fraction of Lycasin HBC in healthy human subjects and their impact on nutrient digestive utilization[J]. Br J Nutr, 2002, 87(2): 131-139. PMID: 11895165. DOI: 10.1079/bjn2001491.
WANG Hui-Min, LIU Chuan-He, LIU Chang-Shan, WANG Ying, HAN Zhi-Ying, SUN Xin, CHEN Xing, AN Shu-Hua, DUOLIKUN Muzhapaer, LU Ai-Ping, WANG Min, CHENG Yan, YIN Xiao-Mei, LIU Han-Min, WANG Hong, HUA Shan, DONG Li, HUANG Ying, JIANG Yi, XIONG Jian-Xin, DING Sheng-Gang, ZHAO Shun-Ying, WANG Jin-Rong, HUANG Gui-Min, MU Jing-Hui, CHEN Yu-Zhi. Efficacy of Huaiqihuang granules as adjuvant therapy for bronchial asthma in children: a real-world study[J]. CJCP, 2021, 23(9): 877-881.
