液体活检在神经母细胞瘤中的临床研究进展

doi:10.7499/j.issn.1008-8830.2112120

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Abstract Neuroblastoma (NB) is the most common extracranial solid tumor in children and has the features of high recurrence rate and low survival rate, and therefore, early diagnosis, treatment response evaluation, and recurrence monitoring are of great significance for NB patients. Liquid biopsy refers to the detection of cells and nucleic acids in fluid specimens, mainly blood. It is noninvasive and can overcome tumor heterogeneity, thus making it possible to achieve the early diagnosis and dynamic detection of NB. This review introduces the latest advances in clinical research on the application of liquid biopsy in NB.

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	LIU Si-Yang
	WEN Fei-Qiu

Key words： Neuroblastoma Liquid biopsy Circulating tumor cell Circulating tumor DNA Exosome Child

Received: 25 December 2021

Cite this article:

LIU Si-Yang,WEN Fei-Qiu. Recent clinical research on the application of liquid biopsy in neuroblastoma[J]. CJCP, 2022, 24(3): 339-344.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2112120 OR http://www.zgddek.com/EN/Y2022/V24/I3/339

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