Changing trend of abdominal regional oxygen saturation in very/extremely low birth weight infants in the early postnatal stage: a prospective study

ZHANG Jing-Hua; GUAN Rui-Lian; PAN Pian-Pian; LU Wei-Neng; ZHANG Hua-Yan

doi:10.7499/j.issn.1008-8830.2105156

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Chinese Journal of Contemporary Pediatrics ›› 2021, Vol. 23 ›› Issue (10) : 1015-1020. DOI: 10.7499/j.issn.1008-8830.2105156

CLINICAL RESEARCH

Changing trend of abdominal regional oxygen saturation in very/extremely low birth weight infants in the early postnatal stage: a prospective study

ZHANG Jing-Hua, GUAN Rui-Lian, PAN Pian-Pian, LU Wei-Neng, ZHANG Hua-Yan

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Abstract

Objective To study the changing trend of abdominal regional oxygen saturation (A-rSO₂) in very/extremely low birth weight (VLBW/ELBW) infants after birth. Methods The VLBW/ELBW infants who were admitted to the neonatal intensive care unit from September 2019 to May 2021 were enrolled as subjects. Near-infrared spectroscopy was used to monitor A-rSO₂ since day 1 after birth for 4 weeks. According to gestational age, the infants were divided into a low gestational age (<29 weeks) group and a high gestational age (≥29 weeks) group. The two groups were compared in terms of A-rSO₂ within 4 weeks after birth. Results A total of 63 VLBW/ELBW infants were enrolled, with 30 infants in the <29 weeks group and 33 in the ≥29 weeks group. A-rSO₂ fluctuated within the first 2 weeks after birth in the 63 infants and had the lowest level of 47.9% on day 1 after birth and then gradually increased, reaching the peak level of 67.4% on day 4; it gradually decreased on days 5-9, then gradually increased, and became relatively stable 2 weeks after birth. The ≥29 weeks group had significantly higher A-rSO₂ than the <29 weeks group at weeks 1 and 2 after birth (P<0.05), while there was no significant difference in A-rSO₂ between the two groups at weeks 3 and 4 after birth (P>0.05). Conclusions In infants with VLBW/ELBW, A-rSO₂ fluctuates within the first 2 weeks after birth and then gradually becomes stable. A-rSO2 is associated with gestational age within 2 weeks after birth.

Key words

Abdominal regional oxygen saturation / Near-infrared spectroscopy / Very low birth weight infant / Extremely low birth weight infant

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ZHANG Jing-Hua, GUAN Rui-Lian, PAN Pian-Pian, LU Wei-Neng, ZHANG Hua-Yan. Changing trend of abdominal regional oxygen saturation in very/extremely low birth weight infants in the early postnatal stage: a prospective study[J]. Chinese Journal of Contemporary Pediatrics. 2021, 23(10): 1015-1020 https://doi.org/10.7499/j.issn.1008-8830.2105156

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