Co-carriage of Streptococcus pneumoniae and Moraxella catarrhalis among preschool children and its influencing factors

DENG Wen-Jun; ZHANG Jing-Feng; LI Ping-Yuan; ZHOU Jun-Li; YAO Zhen-Jiang; YE Xiao-Hua

doi:10.7499/j.issn.1008-8830.2204163

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Chinese Journal of Contemporary Pediatrics ›› 2022, Vol. 24 ›› Issue (8) : 874-880. DOI: 10.7499/j.issn.1008-8830.2204163

CLINICAL RESEARCH

Co-carriage of Streptococcus pneumoniae and Moraxella catarrhalis among preschool children and its influencing factors

DENG Wen-Jun, ZHANG Jing-Feng, LI Ping-Yuan, ZHOU Jun-Li, YAO Zhen-Jiang, YE Xiao-Hua

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Abstract

Objective To investigate the carriage status of Streptococcus pneumoniae (S. pneumoniae) and Moraxella catarrhalis (M. catarrhalis) in preschool children and the influencing factors for the carriage status. Methods The stratified cluster sampling method was used to select 2 031 healthy children from seven kindergartens in Shunde District of Foshan in Guangdong, China. Nasal swabs were collected from all children for the isolation and identification of S. pneumoniae and M. catarrhalis. The carriage status of S. pneumoniae and M. catarrhalis was analyzed in terms of its association with demographic features and hospital- and community-related factors. Results The carriage rates of S. pneumoniae and M. catarrhalis were 21.81% and 52.44%, respectively among the children. The co-carriage rate of S. pneumoniae and M. catarrhalis was 14.87%. The correspondence analysis showed that the factors such as lower grade, non-local registered residence, living in rural areas, small living area, history of respiratory tract infection but no history of antibiotic use, allergic skin diseases, and no hospital-related exposure history were significantly associated with the co-carriage of S. pneumoniae and M. catarrhalis among the children (P<0.05). Conclusions Co-carriage of S. pneumoniae and M. catarrhalis can be observed in preschool children. Young age, poor living environment, a history of respiratory tract infection but no history of antibiotic use, allergic skin diseases, and no hospital-related exposure history are important risk factors for the co-carriage of S. pneumoniae and M. catarrhalis in preschool children.

Key words

Streptococcus pneumoniae / Moraxella catarrhalis / Influencing factor / Child

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DENG Wen-Jun, ZHANG Jing-Feng, LI Ping-Yuan, ZHOU Jun-Li, YAO Zhen-Jiang, YE Xiao-Hua. Co-carriage of Streptococcus pneumoniae and Moraxella catarrhalis among preschool children and its influencing factors[J]. Chinese Journal of Contemporary Pediatrics. 2022, 24(8): 874-880 https://doi.org/10.7499/j.issn.1008-8830.2204163

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