Clinical details in the diagnosis of Kawasaki disease

ZHANG Wei-Hua; SHEN Jie; ZHANG Ya-Le; JIAO Fu-Yong

doi:10.7499/j.issn.1008-8830.2208124

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Chinese Journal of Contemporary Pediatrics ›› 2022, Vol. 24 ›› Issue (12) : 1307-1310. DOI: 10.7499/j.issn.1008-8830.2208124

TOPIC OF KAWASAKI DISEASE

Clinical details in the diagnosis of Kawasaki disease

ZHANG Wei-Hua, SHEN Jie, ZHANG Ya-Le, JIAO Fu-Yong

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Abstract

Kawasaki disease (KD) is one of the leading causes of acquired heart diseases in children aged under 5 years. The clinical manifestations of KD include fever, changes in the extremities, rash or redness at the site of bacille Calmette-Guérin vaccination, bilateral bulbar conjunctival hyperemia, changes in lips and mouth, nonsuppurative cervical lymphadenopathy, and other systemic manifestations. There are difficulties in the diagnosis of KD due to its asynchronous clinical manifestations. With reference to the latest case reports and research advances in KD, this article summarizes the clinical details in the diagnosis of KD, so as to improve the level of clinical diagnosis of KD.

Key words

Kawasaki disease / Diagnosis / Clinical detail / Child

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ZHANG Wei-Hua, SHEN Jie, ZHANG Ya-Le, JIAO Fu-Yong. Clinical details in the diagnosis of Kawasaki disease[J]. Chinese Journal of Contemporary Pediatrics. 2022, 24(12): 1307-1310 https://doi.org/10.7499/j.issn.1008-8830.2208124

References

1 Yale SH, Tekiner H, Yale ES. Tomisaku Kawasaki and Kawasaki disease[J]. Childs Nerv Syst, 2022, 38(2): 233-235. PMID: 32654050. DOI: 10.1007/s00381-020-04784-3.
2 McCrindle BW, Rowley AH, Newburger JW, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association[J]. Circulation, 2017, 135(17): e927-e999. PMID: 28356445. DOI: 10.1161/CIR.0000000000000484.
3 Fukazawa R, Kobayashi J, Ayusawa MMU, et al. JCS/JSCS 2020 guideline on diagnosis and management of cardiovascular sequelae in Kawasaki disease[J]. Circ J, 2020, 84(8): 1348-1407. PMID: 32641591. DOI: 10.1253/circj.CJ-19-1094.
4 Kobayashi T, Ayusawa MMU, Suzuki H, et al. Revision of diagnostic guidelines for Kawasaki disease (6th revised edition)[J]. Pediatr Int, 2020, 62(10): 1135-1138. PMID: 33001522. DOI: 10.1111/ped.14326.
5 Marchesi A, Tarissi de Jacobis I, Rigante D, et al. Kawasaki disease: guidelines of the Italian Society of Pediatrics, part I—definition, epidemiology, etiopathogenesis, clinical expression and management of the acute phase[J]. Ital J Pediatr, 2018, 44(1): 102. PMID: 30157897. PMCID: PMC6116535. DOI: 10.1186/s13052-018-0536-3.
6 中华医学会儿科学分会心血管学组, 中华医学会儿科学分会风湿学组, 中华医学会儿科学分会免疫学组, 等. 川崎病诊断和急性期治疗专家共识[J]. 中华儿科杂志, 2022, 60(1): 6-13. PMID: 34986616. DOI: 10.3760/cma.j.cn112140-20211018-00879.
7 郝胜. 儿童风湿性疾病相关巨噬细胞活化综合征诊断与治疗专家共识之五——川崎病篇[J]. 中国实用儿科杂志, 2020, 35(11): 841-845. DOI: 10.19538/j.ek2020110605.
8 Kainth R, Shah P. Kawasaki disease: origins and evolution[J]. Arch Dis Child, 2021, 106(4): 413-414. PMID: 31628107. DOI: 10.1136/archdischild-2019-317070.
9 Rajandran M, Sharma H, Gupta V, et al. Kawasaki disease without fever: a rare case in a 3-month old[J]. J Paediatr Child Health, 2022, 58(5): 894-895. PMID: 34410020. DOI: 10.1111/jpc.15689.
10 Dimopoulou D, Tsagris V, Georgaki I, et al. Afebrile Kawasaki disease in infants[J]. Minerva Pediatr (Torino), 2021, 73(3): 283-285. PMID: 31271275. DOI: 10.23736/S2724-5276.19.05589-0.
11 Kim JO, Kim YH, Hyun MC. Comparison between Kawasaki disease with lymph-node-first presentation and Kawasaki disease without cervical lymphadenopathy[J]. Korean J Pediatr, 2016, 59(2): 54-58. PMID: 26958063. PMCID: PMC4781732. DOI: 10.3345/kjp.2016.59.2.54.
12 花旺, 龚方戚. 不完全型川崎病临床特征[J]. 中国实用儿科杂志, 2017, 32(8): 572-575. DOI: 10.19538/j.ek2017080604.
13 张清友, 杜军保. 川崎病诊断中的若干问题[J]. 中华实用儿科临床杂志, 2020, 35(13): 961-964. DOI: 10.3760/cma.j.cn101070-20200706-01134.
14 Gupta A, Singh S. Kawasaki disease for dermatologists[J]. Indian Dermatol Online J, 2016, 7(6): 461-470. PMID: 27990380. PMCID: PMC5134159. DOI: 10.4103/2229-5178.193903.
15 Lan YL, Li SX, Yang DH, et al. Clinical characteristics of Kawasaki disease complicated with Mycoplasma pneumoniae pneumonia: a retrospective study[J]. Medicine (Baltimore), 2020, 99(19): e19987. PMID: 32384451. PMCID: PMC7220055.DOI: 10.1097/MD.0000000000019987.
16 张丽. 川崎病的诊断要点[J]. 中国实用儿科杂志, 2017, 32(8): 569-572. DOI: 10.19538/j.ek2017080603.
17 Sosa T, Brower L, Divanovic A. Diagnosis and management of Kawasaki disease[J]. JAMA Pediatr, 2019, 173(3): 278-279. PMID: 30667467. DOI: 10.1001/jamapediatrics.2018.3307.
18 Gámez-González LB. Yamazaki-Nakashimada MA. Erythema multiforme: think Kawasaki disease[J]. J Clin Rheumatol, 2020, 26(6): e181-e182. PMID: 31145225. DOI: 10.1097/RHU.0000000000001055.
19 Pilania RK, Vogeti R, Jindal AK, et al. When beau's lines in the acute phase of Kawasaki disease suggested a disease recurrence: a clinical oddity[J]. J Clin Rheumatol, 2021, 27(6): e228-e229. PMID: 32000224. DOI: 10.1097/RHU.0000000000001324.
20 Kim SH, Lee HJ, Lee JS. Clinical aspects of periungual desquamation in Kawasaki disease[J]. Iran J Pediatr, 2018, 28(3): e59262. DOI: 10.5812/ijp.59262.
21 Chang LS, Weng KP, Yan JH, et al. Desquamation in Kawasaki disease[J]. Children (Basel), 2021, 8(5): 317. PMID: 33919412. PMCID: PMC8143344. DOI: 10.3390/children8050317.
22 Hedrich CM, Schnabel A, Hospach T. Kawasaki disease[J]. Front Pediatr, 2018, 6: 198. PMID:30042935. PMCID: PMC6048561. DOI:10.3389/fped.2018.00198.
23 Uehara R, Igarashi H, Yashiro M, et al. Kawasaki disease patients with redness or crust formation at the bacille calmette-guérin inoculation site[J]. Pediatr Infect Dis J, 2010, 29(5): 430-433. PMID: 20032807. DOI: 10.1097/INF.0b013e3181cacede.
24 Roh DE, Kwon JE, Kim YH. Bacille Calmette-Guérin site reactivation of Kawasaki disease in infants under 3 months of age: relation with diagnosis and prognosis[J]. Children (Basel), 2022, 9(6): 857. PMID: 35740793. PMCID: PMC9222052. DOI: 10.3390/children9060857.
25 Peng Y, Liu XH, Duan Z, et al. Age-related differences in clinical characteristics of Kawasaki disease[J]. Braz J Med Biol Res, 2021, 54(3): e10281. PMID: 33470389. PMCID: PMC7812906. DOI: 10.1590/1414-431X202010281.
26 Gupta A. Kawasaki disease and infections: a myth or a reality?[J]. Indian J Pediatr, 2022, 89(8): 747-748. PMID:35635690. PMCID: PMC9150043. DOI: 10.1007/s12098-022-04284-z.
27 Huang SM, Huang SH, Weng KP, et al. Update on association between Kawasaki disease and infection[J]. J Chin Med Assoc, 2019, 82(3): 172-174. PMID: 30913113. DOI: 10.1097/JCMA.0000000000000025.
28 Singh S, Jindal AK, Pilania RK. Diagnosis of Kawasaki disease[J]. Int J Rheum Dis, 2018, 21(1): 36-44. PMID: 29131549. PMCID: PMC7159575. DOI: 10.1111/1756-185X.13224.
29 Kanegaye JT, Wilder MS, Molkara D, et al. Recognition of a Kawasaki disease shock syndrome[J]. Pediatrics, 2009, 123(5): e783-e789. PMID: 19403470. PMCID: PMC2848476. DOI: 10.1542/peds.2008-1871.
30 刘力. 川崎病休克综合征的早期识别与处理[J]. 中国小儿急救医学, 2020, 27(5): 346-348. DOI: 10.3760/cma.j.issn.1673-4912.2020.05.006.
31 Zhang MM, Shi L, Li XH, et al. Clinical analysis of Kawasaki disease shock syndrome[J]. Chin Med J (Engl), 2017, 130(23): 2891-2892. PMID: 29176153. PMCID: PMC5717875. DOI: 10.4103/0366-6999.219151.
32 黄国英. 川崎病诊断和治疗面临的挑战[J]. 中华儿科杂志, 2022, 60(1): 3-5. PMID: 34986615. DOI: 10.3760/cma.j.cn112140-20211104-00927.