Research progress on long-term developmental outcomes of offspring of pregnant women with systemic lupus erythematosus

SHAO Shu-Ming; ZHANG Yi-Min

doi:10.7499/j.issn.1008-8830.2211036

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Chinese Journal of Contemporary Pediatrics ›› 2023, Vol. 25 ›› Issue (4) : 415-419. DOI: 10.7499/j.issn.1008-8830.2211036

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Research progress on long-term developmental outcomes of offspring of pregnant women with systemic lupus erythematosus

SHAO Shu-Ming, ZHANG Yi-Min

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Abstract

Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease that affects multiple organs and systems. It is more common in women of childbearing age. Compared with the general population, pregnant women with SLE are at a significantly increased risk of adverse perinatal outcomes such as preterm birth and intrauterine growth restriction. In addition, the offspring of SLE patients may also be adversely affected by in utero exposure to maternal autoantibodies, cytokines, and drugs. This article summarizes the long-term developmental outcomes of offspring of pregnant women with SLE in terms of the blood system, circulatory system, nervous system, and immune system. Citation:Chinese Journal of Contemporary Pediatrics, 2023, 25(4): 415-419

Key words

Systemic lupus erythematosus / Pregnancy / Long-term outcome / Offspring

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SHAO Shu-Ming, ZHANG Yi-Min. Research progress on long-term developmental outcomes of offspring of pregnant women with systemic lupus erythematosus[J]. Chinese Journal of Contemporary Pediatrics. 2023, 25(4): 415-419 https://doi.org/10.7499/j.issn.1008-8830.2211036

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