Nutritional status and its influencing factors in children with newly diagnosed inflammatory bowel disease

ZHOU Juan; XIAO Xiong; XIA Yu; YOU Jie-Yu; ZHAO Hong-Mei

doi:10.7499/j.issn.1008-8830.2212066

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Chinese Journal of Contemporary Pediatrics ›› 2023, Vol. 25 ›› Issue (7) : 745-750. DOI: 10.7499/j.issn.1008-8830.2212066

CLINICAL RESEARCH

Nutritional status and its influencing factors in children with newly diagnosed inflammatory bowel disease

ZHOU Juan, XIAO Xiong, XIA Yu, YOU Jie-Yu, ZHAO Hong-Mei

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Abstract

Objective To investigate the nutritional status and its influencing factors in children with newly diagnosed inflammatory bowel disease (IBD). Methods A retrospective analysis was conducted on the clinical data of children who were diagnosed with IBD for the first time in Hunan Children's Hospital from January 2015 to December 2021. Diagnostic delay was defined as the time from the symptom onset to IBD diagnosis being in the upper quartile (P₇₆-P₁₀₀) of all IBD children in the study. Multivariate logistic regression analysis was used to explore the risk factors for emaciation and growth retardation. Results A total of 125 children with newly diagnosed IBD were included, with Crohn's disease being the main type (91.2%). The rates of emaciation and growth retardation were 42.4% (53 cases) and 7.2% (9 cases), respectively, and the rate of anemia was 77.6% (97 cases). Diagnostic delay was noted in 31 children (24.8%), with the time from the symptom onset to IBD diagnosis of 366 to 7 211 days. Multivariate logistic regression analysis showed that diagnostic delay was a risk factor for emaciation and growth retardation (OR=2.73 and OR=4.42, respectively; P<0.05) and that age was positively associated with emaciation (OR=1.30, P<0.05). Conclusions Children with newly diagnosed IBD have poor nutritional status, and the rates of anemia, emaciation, and growth retardation are high. Diagnostic delay is associated with malnutrition in children with IBD.

Key words

Inflammatory bowel disease / Diagnostic delay / Anemia / Emaciation / Growth retardation / Child

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ZHOU Juan, XIAO Xiong, XIA Yu, YOU Jie-Yu, ZHAO Hong-Mei. Nutritional status and its influencing factors in children with newly diagnosed inflammatory bowel disease[J]. Chinese Journal of Contemporary Pediatrics. 2023, 25(7): 745-750 https://doi.org/10.7499/j.issn.1008-8830.2212066

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