References
1 Sendinc E, Shi Y. RNA m6A methylation across the transcriptome[J]. Mol Cell, 2023, 83(3): 428-441. PMID: 36736310. DOI: 10.1016/j.molcel.2023.01.006.
2 Garbo S, Zwergel C, Battistelli C. m6A RNA methylation and beyond: the epigenetic machinery and potential treatment options[J]. Drug Discov Today, 2021, 26(11): 2559-2574. PMID: 34126238. DOI: 10.1016/j.drudis.2021.06.004.
3 Jiang X, Stockwell BR, Conrad M. Ferroptosis: mechanisms, biology and role in disease[J]. Nat Rev Mol Cell Biol, 2021, 22(4): 266-282. PMID: 33495651. PMCID: PMC8142022. DOI: 10.1038/s41580-020-00324-8.
4 GBD Chronic Respiratory Disease Collaborators. Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease study 2017[J]. Lancet Respir Med, 2020, 8(6): 585-596. PMID: 32526187. PMCID: PMC7284317. DOI: 10.1016/S2213-2600(20)30105-3.
5 Mo BW, Li XM, Li SM, et al. m6A echoes with DNA methylation: coordinated DNA methylation and gene expression data analysis identified critical m6A genes associated with asthma[J]. Gene, 2022, 828: 146457. PMID: 35421547. DOI: 10.1016/j.gene.2022.146457.
6 Tang W, Dong M, Teng F, et al. TMT-based quantitative proteomics reveals suppression of SLC3A2 and ATP1A3 expression contributes to the inhibitory role of acupuncture on airway inflammation in an OVA-induced mouse asthma model[J]. Biomed Pharmacother, 2021, 134: 111001. PMID: 33341053. DOI: 10.1016/j.biopha.2020.111001.
7 Tang H, Li T, Han X, et al. TLR4 antagonist ameliorates combined allergic rhinitis and asthma syndrome (CARAS) by reducing inflammatory monocytes infiltration in mice model[J]. Int Immunopharmacol, 2019, 73: 254-260. PMID: 31121415. DOI: 10.1016/j.intimp.2019.05.021.
8 中国妇幼保健协会儿童变态反应专业委员会, 《中国实用儿科杂志》编辑委员会. 儿童变应性鼻炎-哮喘综合征中西医结合诊治专家共识(2023)[J]. 中国实用儿科杂志, 2023, 38(3): 168-176. DOI: 10.19538/j.ek2023030602.
9 Grossman J. One airway, one disease[J]. Chest, 1997, 111(2 Suppl): 11S-16S. PMID: 9042022. DOI: 10.1378/chest.111.2_supplement.11s.
10 Pawankar R, Canonica G, Holgate S, et al. WAO White Book on Allergy 2011-2012: Executive Summary[EB/OL]. (2012-04-23) [2022-10-16]. http://isir.ru/files/WAO_White_Book-Summary.pdf.
11 Paiva Ferreira LKD, Paiva Ferreira LAM, Monteiro TM, et al. Combined allergic rhinitis and asthma syndrome (CARAS)[J]. Int Immunopharmacol, 2019, 74: 105718. PMID: 31255882. DOI: 10.1016/j.intimp.2019.105718.
12 Niu Y, Zhao X, Wu YS, et al. N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function[J]. Genomics Proteomics Bioinformatics, 2013, 11(1): 8-17. PMID: 23453015. PMCID: PMC4357660. DOI: 10.1016/j.gpb.2012.12.002.
13 Satterwhite ER, Mansfield KD. RNA methyltransferase METTL16: targets and function[J]. Wiley Interdiscip Rev RNA, 2022, 13(2): e1681. PMID: 34227247. PMCID: PMC9286414. DOI: 10.1002/wrna.1681.
14 Wang P, Doxtader KA, Nam Y. Structural basis for cooperative function of Mettl3 and Mettl14 methyltransferases[J]. Mol Cell, 2016, 63(2): 306-317. PMID: 27373337. PMCID: PMC4958592. DOI: 10.1016/j.molcel.2016.05.041.
15 Yang B, Wang JQ, Tan Y, et al. RNA methylation and cancer treatment[J]. Pharmacol Res, 2021, 174: 105937. PMID: 34648969. DOI: 10.1016/j.phrs.2021.105937.
16 Liao J, Wei Y, Liang J, et al. Insight into the structure, physiological function, and role in cancer of m6A readers-YTH domain-containing proteins[J]. Cell Death Discov, 2022, 8(1): 137. PMID: 35351856. PMCID: PMC8964710. DOI: 10.1038/s41420-022-00947-0.
17 Lu SC. S-adenosylmethionine[J]. Int J Biochem Cell Biol, 2000, 32(4): 391-395. PMID: 10762064. DOI: 10.1016/s1357-2725(99)00139-9.
18 Xu Z, Lv B, Qin Y, et al. Emerging roles and mechanism of m6A methylation in cardiometabolic diseases[J]. Cells, 2022, 11(7): 1101. PMID: 35406663. PMCID: PMC8997388. DOI: 10.3390/cells11071101.
19 Liu L, Li H, Hu D, et al. Insights into N6-methyladenosine and programmed cell death in cancer[J]. Mol Cancer, 2022, 21(1): 32. PMID: 35090469. PMCID: PMC8796496. DOI: 10.1186/s12943-022-01508-w.
20 Cavalcanti RFP, Gadelha FAAF, de Jesus TG, et al. Warifteine and methylwarifteine inhibited the type 2 immune response on combined allergic rhinitis and asthma syndrome (CARAS) experimental model through NF-кB pathway[J]. Int Immunopharmacol, 2020, 85: 106616. PMID: 32450529. DOI: 10.1016/j.intimp.2020.106616.
21 Wang Y, Wang J, Yan Z, et al. Microenvironment modulation by key regulators of RNA N6-methyladenosine modification in respiratory allergic diseases[J]. BMC Pulm Med, 2023, 23(1): 210. PMID: 37328853. PMCID: PMC10276419. DOI: 10.1186/s12890-023-02499-0.
22 Fan Y, Yang C, Zhou J, et al. Regulatory effect of glutathione on Treg/Th17 cell balance in allergic rhinitis patients through inhibiting intracellular autophagy[J]. Immunopharmacol Immunotoxicol, 2021, 43(1): 58-67. PMID: 33285073. DOI: 10.1080/08923973.2020.1850762.
23 Stone KD, Prussin C, Metcalfe DD. IgE, mast cells, basophils, and eosinophils[J]. J Allergy Clin Immunol, 2010, 125(2 Suppl 2): S73-S80. PMID: 20176269. PMCID: PMC2847274. DOI: 10.1016/j.jaci.2009.11.017.
24 Saradna A, Do DC, Kumar S, et al. Macrophage polarization and allergic asthma[J]. Transl Res, 2018, 191: 1-14. PMID: 29066321. PMCID: PMC5776696. DOI: 10.1016/j.trsl.2017.09.002.
25 Han X, Liu L, Huang S, et al. RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis[J]. Nat Commun, 2023, 14(1): 7328. PMID: 37957139. PMCID: PMC10643624. DOI: 10.1038/s41467-023-43219-w.
26 Dai B, Sun F, Cai X, et al. Significance of RNA N6-methyladenosine regulators in the diagnosis and subtype classification of childhood asthma using the gene expression omnibus database[J]. Front Genet, 2021, 12: 634162. PMID: 33763115. PMCID: PMC7982807. DOI: 10.3389/fgene.2021.634162.
27 Li HB, Tong J, Zhu S, et al. m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways[J]. Nature, 2017, 548(7667): 338-342. PMID: 28792938. PMCID: PMC5729908. DOI: 10.1038/nature23450.
28 Asayama K, Kobayashi T, D'Alessandro-Gabazza CN, et al. Protein S protects against allergic bronchial asthma by modulating Th1/Th2 balance[J]. Allergy, 2020, 75(9): 2267-2278. PMID: 32145080. DOI: 10.1111/all.14261.
29 Wang J, Jian Q, Yan K, et al. m6A-modified miR-143-3p inhibits epithelial mesenchymal transition in bronchial epithelial cells and extracellular matrix production in lung fibroblasts by targeting Smad3[J]. Pulm Pharmacol Ther, 2023, 83: 102251. PMID: 37666296. DOI: 10.1016/j.pupt.2023.102251.
30 Teng F, Tang W, Wuniqiemu T, et al. N6-methyladenosine methylomic landscape of lung tissues in murine acute allergic asthma[J]. Front Immunol, 2021, 12: 740571. PMID: 34737744. PMCID: PMC8560743. DOI: 10.3389/fimmu.2021.740571.
31 Li J, Cao F, Yin HL, et al. Ferroptosis: past, present and future[J]. Cell Death Dis, 2020, 11(2): 88. PMID: 32015325. PMCID: PMC6997353. DOI: 10.1038/s41419-020-2298-2.
32 Stockwell BR. Ferroptosis turns 10: emerging mechanisms, physiological functions, and therapeutic applications[J]. Cell, 2022, 185(14): 2401-2421. PMID: 35803244. PMCID: PMC9273022. DOI: 10.1016/j.cell.2022.06.003.
33 Tang D, Chen X, Kang R, et al. Ferroptosis: molecular mechanisms and health implications[J]. Cell Res, 2021, 31(2): 107-125. PMID: 33268902. PMCID: PMC8026611. DOI: 10.1038/s41422-020-00441-1.
34 Chen X, Kang R, Kroemer G, et al. Broadening horizons: the role of ferroptosis in cancer[J]. Nat Rev Clin Oncol, 2021, 18(5): 280-296. PMID: 33514910. DOI: 10.1038/s41571-020-00462-0.
35 Sun Y, Chen P, Zhai B, et al. The emerging role of ferroptosis in inflammation[J]. Biomed Pharmacother, 2020, 127: 110108. PMID: 32234642. DOI: 10.1016/j.biopha.2020.110108.
36 Liang C, Zhang X, Yang M, et al. Recent progress in ferroptosis inducers for cancer therapy[J]. Adv Mater, 2019, 31(51): e1904197. PMID: 31595562. DOI: 10.1002/adma.201904197.
37 Yu S, Jia J, Zheng J, et al. Recent progress of ferroptosis in lung diseases[J]. Front Cell Dev Biol, 2021, 9: 789517. PMID: 34869391. PMCID: PMC8635032. DOI: 10.3389/fcell.2021.789517.
38 Shou Y, Yang L, Yang Y, et al. Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation[J]. Cell Death Dis, 2021, 12(11): 1009. PMID: 34707088. PMCID: PMC8551323. DOI: 10.1038/s41419-021-04284-5.
39 Gu W, Hou T, Zhou H, et al. Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy[J]. Int Immunopharmacol, 2023, 115: 109658. PMID: 36608444. DOI: 10.1016/j.intimp.2022.109658.
40 Nakamura Y, Fuse Y, Komiyama S, et al. Dietary iodine attenuates allergic rhinitis by inducing ferroptosis in activated B cells[J]. Sci Rep, 2023, 13(1): 5398. PMID: 37012320. PMCID: PMC10070403. DOI: 10.1038/s41598-023-32552-1.
41 Nagasaki T, Schuyler AJ, Zhao J, et al. 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation[J]. J Clin Invest, 2022, 132(1): e151685. PMID: 34762602. PMCID: PMC8718153. DOI: 10.1172/JCI151685.
42 Wenzel SE, Tyurina YY, Zhao J, et al. PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals[J]. Cell, 2017, 171(3): 628-641.e26. PMID: 29053969. PMCID: PMC5683852. DOI: 10.1016/j.cell.2017.09.044.
43 Han F, Li S, Yang Y, et al. Interleukin-6 promotes ferroptosis in bronchial epithelial cells by inducing reactive oxygen species-dependent lipid peroxidation and disrupting iron homeostasis[J]. Bioengineered, 2021, 12(1): 5279-5288. PMID: 34402724. PMCID: PMC8806540. DOI: 10.1080/21655979.2021.1964158.
44 Yu T, Yu Y, Ma Y, et al. Inhibition of CREB promotes glucocorticoids action on airway inflammation in pediatric asthma by promoting ferroptosis of eosinophils[J]. Allergol Immunopathol (Madr), 2023, 51(4): 164-174. PMID: 37422794. DOI: 10.15586/aei.v51i4.873.
45 Liu C, Wu X, Bing X, et al. H1N1 influenza virus infection through NRF2-KEAP1-GCLC pathway induces ferroptosis in nasal mucosal epithelial cells[J]. Free Radic Biol Med, 2023, 204: 226-242. PMID: 37146698. DOI: 10.1016/j.freeradbiomed.2023.05.004.
46 Liu J, Xu Y, Yan M, et al. 18β-glycyrrhetinic acid suppresses allergic airway inflammation through NF-κB and Nrf2/HO-1 signaling pathways in asthma mice[J]. Sci Rep, 2022, 12(1): 3121. PMID: 35210449. PMCID: PMC8873505. DOI: 10.1038/s41598-022-06455-6.
47 Rochette L, Dogon G, Rigal E, et al. Lipid peroxidation and iron metabolism: two corner stones in the homeostasis control of ferroptosis[J]. Int J Mol Sci, 2022, 24(1): 449. PMID: 36613888. PMCID: PMC9820499. DOI: 10.3390/ijms24010449.
48 Nishida Xavier da Silva T, Friedmann Angeli JP, Ingold I. GPX4: old lessons, new features[J]. Biochem Soc Trans, 2022, 50(3): 1205-1213. PMID: 35758268. DOI: 10.1042/BST20220682.
49 Lin L, Hu X, Li Q, et al. Methyltransferase-like 3 (METTL3) epigenetically modulates glutathione peroxidase 4 (GPX4) expression to affect asthma[J]. Iran J Allergy Asthma Immunol, 2023, 22(6): 551-560. PMID: 38477952. DOI: 10.18502/ijaai.v22i6.14644.
50 Gani F, Cottini M, Landi M, et al. Allergic rhinitis and COVID-19: friends or foes?[J]. Eur Ann Allergy Clin Immunol, 2022, 54(2): 53-59. PMID: 34503647. DOI: 10.23822/EurAnnACI.1764-1489.234.
51 Leynaert B, Neukirch F, Demoly P, et al. Epidemiologic evidence for asthma and rhinitis comorbidity[J]. J Allergy Clin Immunol, 2000, 106(5 Suppl): S201-S205. PMID: 11080732. DOI: 10.1067/mai.2000.110151.