Research progress on toxic shock syndrome due to group A Streptococcus infection in children

Hong-Yu WANG, Wei ZHOU, Li-Su HUANG

Chinese Journal of Contemporary Pediatrics ›› 2026, Vol. 28 ›› Issue (1) : 120-127.

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Chinese Journal of Contemporary Pediatrics ›› 2026, Vol. 28 ›› Issue (1) : 120-127. DOI: 10.7499/j.issn.1008-8830.2503136
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Research progress on toxic shock syndrome due to group A Streptococcus infection in children

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Abstract

Streptococcal toxic shock syndrome in children is a severe complication of group A Streptococcus infection, characterized by acute shock and multiple organ dysfunction. It is a critical illness with high mortality, and early diagnosis and treatment are key to improving prognosis. Children with this syndrome have a higher risk of death, and the pathogenesis is complex. This review summarizes the pathogenesis and recent advances in the diagnosis and treatment of streptococcal toxic shock syndrome caused by group A Streptococcus infection in children, aiming to improve clinical outcomes and reduce mortality.

Key words

Streptococcal toxic shock syndrome / Group A Streptococcus / Treatment / Child

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Hong-Yu WANG , Wei ZHOU , Li-Su HUANG. Research progress on toxic shock syndrome due to group A Streptococcus infection in children[J]. Chinese Journal of Contemporary Pediatrics. 2026, 28(1): 120-127 https://doi.org/10.7499/j.issn.1008-8830.2503136

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