PDF(892 KB)
Duchenne muscular dystrophy-associated cardiomyopathy: advances in diagnosis and management
Jie GU, Yu-Hang LIU, Si-Qi HONG
Chinese Journal of Contemporary Pediatrics ›› 2026, Vol. 28 ›› Issue (10) : 1289-1297.
PDF(892 KB)
PDF(892 KB)
Duchenne muscular dystrophy-associated cardiomyopathy: advances in diagnosis and management
Duchenne muscular dystrophy (DMD) is an X-linked recessive neuromuscular disorder in which cardiac involvement is relatively insidious, and heart failure has become one of the major determinants of prognosis. Cardiac magnetic resonance imaging and speckle-tracking echocardiography provide a basis for the precise assessment of DMD-associated cardiomyopathy. At present, glucocorticoid therapy and cardiovascular drug therapy are the basic treatment approaches, and gene therapy, cell therapy, and molecularly targeted drugs are continually evolving. This review summarizes pathogenic mechanisms, diagnostic techniques, and therapeutic strategies for DMD-associated cardiomyopathy, with the aim of informing standardized clinical management and improving patient quality of life.
Duchenne muscular dystrophy / Cardiomyopathy / Cardiac magnetic resonance imaging / Cardiovascular agent
| [1] |
中华医学会罕见病分会, 北京医学会罕见病分会. Duchenne型肌营养不良多学科管理指南[J]. 中华内科杂志, 2025, 64(9): 812-824. DOI: 10.3760/cma.j.cn112138-20250412-00210 .
|
| [2] |
|
| [3] |
|
| [4] |
|
| [5] |
|
| [6] |
|
| [7] |
|
| [8] |
|
| [9] |
|
| [10] |
|
| [11] |
|
| [12] |
|
| [13] |
|
| [14] |
|
| [15] |
|
| [16] |
|
| [17] |
|
| [18] |
张琳玲, 王川, 谢佩环, 等. 杜氏肌营养不良男性患儿486份心电图特征病例系列报告[J]. 中国循证儿科杂志, 2023, 18(4): 255-260. DOI: 10.3969/j.issn.1673-5501.2023.04.002 .
|
| [19] |
|
| [20] |
|
| [21] |
|
| [22] |
|
| [23] |
|
| [24] |
|
| [25] |
|
| [26] |
姚凤娟, 郑菊, 陆堃, 等. 血流多普勒Tei指数对进行性肌营养不良患者左心功能的探讨[J]. 影像诊断与介入放射学, 2007, 16(5): 203-205. DOI: 10.3969/j.issn.1005-8001.2007.05.004 .
|
| [27] |
|
| [28] |
|
| [29] |
|
| [30] |
|
| [31] |
|
| [32] |
|
| [33] |
|
| [34] |
|
| [35] |
|
| [36] |
|
| [37] |
|
| [38] |
|
| [39] |
|
| [40] |
|
| [41] |
|
| [42] |
|
| [43] |
|
| [44] |
|
| [45] |
|
| [46] |
|
| [47] |
|
| [48] |
|
| [49] |
|
| [50] |
|
| [51] |
|
| [52] |
|
| [53] |
|
| [54] |
|
| [55] |
|
| [56] |
|
所有作者声明无利益冲突。