Nasal carriage of community-acquired methicillin-resistant Staphylococcus aureus in healthy children from Chengdu

FAN  Juan; ZHOU  Wei; SHU  Min; DENG  Jian-Jun; ZHU  Yu; DENG  Si-Yan; GUO  Qin; WAN  Chao-Min

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Chinese Journal of Contemporary Pediatrics ›› 2011, Vol. 13 ›› Issue (1) : 16-19.

CLINICAL RESEARCH

Nasal carriage of community-acquired methicillin-resistant Staphylococcus aureus in healthy children from Chengdu

FAN Juan, ZHOU Wei, SHU Min, DENG Jian-Jun, ZHU Yu, DENG Si-Yan, GUO Qin, WAN Chao-Min

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Abstract

OBJECTIVE: To evaluate the prevalence of nasal carriage of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in healthy children from Chengdu. METHODS: Strains of Staphylococcus aureus were isolated from nasal swabs of healthy children from five kindergartens in Chengdu from September, 2005 to December, 2005 and questionnaires were obtained. Antibiotic susceptibility test was performed with agar disk diffusion and Bauer-Kirby on Mueller-Hinton medium method to determine CA-MRSA. mecA and PVL genes were detected with PCR in all of the CA-MRSA isolates. RESULTS: A total of 801 children were enrolled. Overall 147 children (18.4%) were carried with Staphylococcus aureus and 9 (1.1%) were carried with CA-MRSA. All CA-MRSA isolates were positive for mecA gene, and 5 CA-MRSA isolates were positive for PVL gene. Of the 9 CA-MRSA isolates, 6 were multiresistant. CONCLUSIONS: CA-MRSA nasal colonization is present among Chengdu healthy children. The CA-MRSA isolates are multiresistant and parts of CA-MRSA isolates carry PVL gene. The nasal carriage of CA-MRSA in healthy children should be a concerned issue.

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Community-acquired methicillin-resistant Staphylococcus aureus / Carriage / Child

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FAN Juan, ZHOU Wei, SHU Min, DENG Jian-Jun, ZHU Yu, DENG Si-Yan, GUO Qin, WAN Chao-Min. Nasal carriage of community-acquired methicillin-resistant Staphylococcus aureus in healthy children from Chengdu[J]. Chinese Journal of Contemporary Pediatrics. 2011, 13(1): 16-19

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