Relationship between congenital heart disease and bronchial dysplasia

ZENG Shuang-Lin; LI Ya-Jun; HUANG Ting; TAN Li-Hua; MEI Xi-Long; SUN Jian-Ning

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Chinese Journal of Contemporary Pediatrics ›› 2011, Vol. 13 ›› Issue (11) : 893-895.

CLINICAL RESEARCH

Relationship between congenital heart disease and bronchial dysplasia

ZENG Shuang-Lin, LI Ya-Jun, HUANG Ting, TAN Li-Hua, MEI Xi-Long, SUN Jian-Ning

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Abstract

OBJECTIVE: To study the relationship of the incidence of bronchial dysplasia (bronchial anomalous origin and bronchial stenosis) with congenital heart disease. METHODS: A total of 185 children with congenital heart disease or bronchial dysplasia were enrolled. Bronchial dysplasia was identified by the 64-MSCT conventional scanning or thin slice scanning with three-dimensional reconstruction. RESULTS: Forty-five children (25.3%) had coexisting bronchial dysplasia and congenital heart disease. The incidence rate of bronchial dysplasia in children with congenital heart disease associated with ventricular septal defect was higher than in those without ventricular septal defect (33.7% vs 15.0%; P<0.05). There were no significant differences in the incidence rate of bronchial dysplasia between the children with congenital heart disease who had a large vascular malformation and who did not. CONCLUSIONS: Bronchial dysplasia often occurs in children with congenital heart disease. It is necessary to perform a tracheobronchial CT scanning with three-dimensional reconstruction to identify tracheobronchial dysplasia in children with congenital heart disease, especially associated with ventricular septal defect.

Key words

Congenital heart disease / Bronchial dysplasia / Computed tomography / Child

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ZENG Shuang-Lin, LI Ya-Jun, HUANG Ting, TAN Li-Hua, MEI Xi-Long, SUN Jian-Ning. Relationship between congenital heart disease and bronchial dysplasia[J]. Chinese Journal of Contemporary Pediatrics. 2011, 13(11): 893-895

References

［1］Ghaye B, Szapiro D, Fanchamps JM, Dondelinger RF. Congenital bronchial abnormalities revisited［J］.Radiographics,2001,21(1):105-119.

［2］王荣品,梁长虹,黄美萍,刘辉,崔燕海,刘其顺.儿童先天性心脏病伴气管支气管狭窄的多层螺旋CT诊断［J］.中国放射学杂志,2010,44(8):811-815.

［3］Ekhard E, Ziegler LJ, Flier Jr.现代营养学［M］.第7版.闻芝梅, 陈君石译.北京:人民卫生出版社,1998：108.

［4］Morriss-Kay GM,Sokolova N.Embryonic development and pattern formation［J］. FASEB J,1996,10(9):961-968.

［5］Brand T.Heart development: molecular insights into cardiac specification and early morphogenesis［J］.Dev Biol, 2003, 258(1): 1-19.

［6］Sieber-Blum M. Cardiac neural crest stem cells［J］.Anat Rec A Discov Mol Cell Evol Biol, 2004, 276(1): 34-42.

［7］Small EM, Krieg PA. Molecular regulation of cardiac chamber-specific gene expression［J］.Trends Cardiovasc Med,2004,14(1):13-18.

［8］薛潋滟,朱铭,杜隽,仲卿雯,邵虹,施美华.小儿先天性心脏病伴支气狭窄的影像学诊断［J］.中国医学影像技术,2006,22(7):1009-1011.

［9］Yama N, Koito K, Hareyama M, Nara S, Okamoto H, Kurimoto Y, et al. Tracheal bronchus mimicking bronchial intubation endoscopically: report of a case with airway burn［J］. Am J Emerg Med, 2005, 23(6): 815-816.

［10］Munro HM, Sorbello AM, Nykanen DG. Severe stenosis of a long tracheal segment, with agenesis of the right lung and left pulmonary arterial sling［J］. Cardiol Young, 2006, 16(1): 89-91.

［11］McLaughlin FJ, Strieder DJ, Harris GB, Vawter GP, Eraklis AJ. Tracheal bronchus association with respiratory morbidity in childhood［J］. J Pediatr, 1985, 106(5): 751-755.

［12］Loukanov T,Sebening C,Springer W,Ulmer H,Hagl S.Simultaneous managemen of congenital tracheal stenosis and cardiac anomalies in infants［J］.J Thorac ardiovasc Surg,2005,130 (6):1537-1541.

［13］殷勇,王薇.儿童气管性支气管诊断、分类和气道管理的临床研究［J］.中国小儿急救医学,2007,14(5):403-406.

［14］方必东,王毅,赵晓君,许崇永,赵雅萍,程建敏，等.多层CT容积漫游技术在先天性气管支气管狭窄的诊断价值［J］.医学影像学杂,2008,18(10):1128-1130.

［15］殷勇,陆奕,肖洁,岳孟源,王薇.螺旋CT三维成像对儿童气管狭窄的诊断价值［J］.中国当代儿科杂志,2005,7(4):376-377.