Risk factors for patent ductus arteriosus in neonates

QU Xiao-Yu; ZHOU Xian-Feng; QU Yi; TANG Bin-Zhi; MU De-Zhi

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Chinese Journal of Contemporary Pediatrics ›› 2011, Vol. 13 ›› Issue (5) : 388-391.

CLINICAL RESEARCH

Risk factors for patent ductus arteriosus in neonates

QU Xiao-Yu, ZHOU Xian-Feng, QU Yi, TANG Bin-Zhi, MU De-Zhi

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Abstract

OBJECTIVE: To identify the risk factors for patent ductus arteriosus (PDA) in neonates. METHODS: Fifty infants with PDA and 100 infants without PDA were enrolled. Chi-square test, Student′s t test and the linear correlation analysis were used to study the clinical data. Logistic regression analysis was used to investigate the independent risk factors for PDA. RESULTS: The prevalence of PDA was negatively correlated with the gestation age (r=-0.03, P<0.05) and birth weight (r=-0.04, P<0.05). Oxygen inhalation was a protective factor for the development of PDA. Fetal distress, meconium-stained amniotic fluid, oligohydramnios, cord entanglement, 1 minute Apgar score<8, maternal infection and hypoxic-ischemic encephalopathy were the independent risk factors for the development of PDA. CONCLUSIONS: The incidence of PDA can be reduced by preventing maternal infection, premature birth, low birth weight and hypoxia.

Key words

Patent ductus arteriosus / Risk factor / Neonate

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QU Xiao-Yu, ZHOU Xian-Feng, QU Yi, TANG Bin-Zhi, MU De-Zhi. Risk factors for patent ductus arteriosus in neonates[J]. Chinese Journal of Contemporary Pediatrics. 2011, 13(5): 388-391

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