［1］黄东明，肖晓雄，何晓玲，崔碧云，汪叶红，李小琳，等.学龄儿童支气管哮喘危险因素的调查［J］. 中国当代儿科杂志，2011，13(5)：370-372.

［2］Umetsu DT. Hygiene revisited: Microbes, apoptosis and TIM-1 in the development of asthma［J］. Paediatr Res Rev, 2010, 11(Suppl 1): S3.

［3］全国儿童哮喘防治协作组. 中国城区儿童哮喘患病率调查［J］. 中华儿科杂志，2003，41(2)：123-127.

［4］Cookson W. Genetics and genomics of asthma and allergic diseases［J］. Immunol Rev, 2002, 190: 195-206.

［5］McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, et al. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family［J］. Nat Immunol, 2001, 2(12): 1109-1116.

［6］Freeman GJ, Casasnovas JM, Umetsu DT, DeKruyff RH. TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity［J］. Immunol Rev, 2010, 235(1): 172-189.

［7］Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, Slavik J, Kassam N, Dardalhon V, et al. TIM-4 expressed on APCs induces T cell expansion and survival［J］. J Immunol, 2008, 180(7): 4706-4713.

［8］Umetsu SE, Lee WL, McIntire JJ, Downey L, Sanjanwala B, Akbari O, et al. TIM-1 induces T cell activation and inhibits the development of peripheral tolerance［J］. Nature Immunol, 2005, 6(5): 447-454.

［9］Meyers JH, Chakravarti S, Schlesinger D, Illes Z, Waldner H, Umetsu SE, et al. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation［J］. Nature Immunol, 2005, 6(5): 455-464.

［10］Nakajima T, Wooding S, Satta Y, Jinnai N, Goto S, Hayasaka I, et al. Evidence for natural selection in the HAVCR1 gene: high degree of amino-acid variability in the mucin domain of human HAVCR1 protein［J］. Genes Immun, 2005, 6(5): 398-406.

［11］中华医学会儿科学分会呼吸学组. 儿童支气管哮喘防治常规(试行)［J］. 中华儿科杂志，2004，42(2)：100-106.

［12］Ghecham A. TIM-4基因多态性与中国汉族人群哮喘的相关性研究 ［D］.山东大学，2009.

［13］夏义平. TIM-4基因多态性与变应性哮喘的相关性研究 ［D］.华中科技大学，2007.

［14］吴小慧, 李一荣, 陈请国, 陈凤花, 胡丽华. TIM-4基因多态性与湖北地区汉族人群支气管哮喘易感性的研究［J］. 中华微生物学和免疫学杂志，2008，29(9)：833-837.

［15］蔡鹏程. TIM-4基因多态性与变应性哮喘关系的病例对照及家系研究 ［D］.华中科技大学，2009.