OBJECTIVE: To study the changes of compliance (CRS) and resistance of the respiratory system (RRS) in infants with pneumonia. METHODS: Seventy nine infants with pneumonia were assigned into two age groups: under 6 months group and over 6 months group. Each group of infants were further assigned into two case groups: severe pneumonia group (n=27) and mild pneumonia group (n=52). Thirty two healthy infants served as controls. CRS and RRS were measured using the passive expiratory flow volume technique (PFV). RESULTS: In the under 6 months group, CRS of the severe pneumonia group, mild pneumonia group and the controls were ( 0.003 ± 0.0008 ), ( 0.004 ± 0.001 ) and ( 0.017 ± 0.005 ) L/kPa, respectively. RRS of the severe pneumonia group, mild pneumonia group and the controls were ( 10.14 ± 1.01 ), ( 9.09 ± 2.32 ) and ( 3.61 ± 0.76 ) kPa·s/L, respectively. There were significant differences in CRS and RRS among the three groups (P< 0.05 ). In the over 6 months group, CRS of the severe pneumonia group, mild pneumonia group and the controls were ( 0.006 ± 0.002 ), ( 0.011 ± 0.002 ) and ( 0.020 ± 0.005 ) L/kPa, respectively. RRS of the severe pneumonia group, mild pneumonia group and the controls were ( 2.05 ± 0.55 ), ( 1.61 ± 0.37 ) and ( 1.11 ± 0.23 ) kPa·s/L, respectively. There were significant differences in CRS and RRS among the three groups (P< 0.05 ). CONCLUSIONS: CRS decreased and RRS increased in infants with pneumonia. Moreover, the more serious the pneumonia, the more significant the changes."/>
婴儿肺炎呼吸系统顺应性及阻力的被动流速容量测定
Abstract：OBJECTIVE: To study the changes of compliance (CRS) and resistance of the respiratory system (RRS) in infants with pneumonia. METHODS: Seventy nine infants with pneumonia were assigned into two age groups: under 6 months group and over 6 months group. Each group of infants were further assigned into two case groups: severe pneumonia group (n=27) and mild pneumonia group (n=52). Thirty two healthy infants served as controls. CRS and RRS were measured using the passive expiratory flow volume technique (PFV). RESULTS: In the under 6 months group, CRS of the severe pneumonia group, mild pneumonia group and the controls were ( 0.003 ± 0.0008 ), ( 0.004 ± 0.001 ) and ( 0.017 ± 0.005 ) L/kPa, respectively. RRS of the severe pneumonia group, mild pneumonia group and the controls were ( 10.14 ± 1.01 ), ( 9.09 ± 2.32 ) and ( 3.61 ± 0.76 ) kPa·s/L, respectively. There were significant differences in CRS and RRS among the three groups (P< 0.05 ). In the over 6 months group, CRS of the severe pneumonia group, mild pneumonia group and the controls were ( 0.006 ± 0.002 ), ( 0.011 ± 0.002 ) and ( 0.020 ± 0.005 ) L/kPa, respectively. RRS of the severe pneumonia group, mild pneumonia group and the controls were ( 2.05 ± 0.55 ), ( 1.61 ± 0.37 ) and ( 1.11 ± 0.23 ) kPa·s/L, respectively. There were significant differences in CRS and RRS among the three groups (P< 0.05 ). CONCLUSIONS: CRS decreased and RRS increased in infants with pneumonia. Moreover, the more serious the pneumonia, the more significant the changes.
JIANG Wen-Hui,DENG Li,WEN Hui-Hong et al. Determination of Compliance and Resistance of the Respiratory System Using the Passive Expiratory Flow Volume Technique in Infants with Pneumonia[J]. CJCP, 2002, 4(5): 380-382.
