Abstract：OBJECTIVE: To explore the Infant Neurological International Battery (Infanib) as a screening tool for early detection of gross motor developmental delay in preterm infants discharged from NICU, and to predict their later neuromotor dysfunction (cerebral palsy or motor retardation). METHODS: A cohort of preterm infants who were admitted to the neonatal intensive care unit between June 2008 and March 2010 were enrolled in the study. Infanib assessment was performed at corrected age 3-4 months and 6-7 months. Peabody Developmental Motor scale-2 (PDMS-2) and neuro-examinations were used to confirm the last motor retardation. The sensitivity, specificity, positive predictive value and negative predictive value of the Infanib were calculated.ResultsA total of 147 preterm infants were participated in this study, and 129 infants were followed up at correct age 12 months or more than 12 months. Eleven (8.5%) had crerbral palsy, 28 (21.7%) had motor retardation, and 90 (69.8%) normal mortor development. The predictive validity of the Infanib at correct age 3-4 months (n=14) was: sensitivity 84.6%, specificity 75.6%, positive predictive value 60.0% and negative predictive value 91.9%. The predictive validity of the Infanib at correct age 6-7 months (n=117) was: sensitivity 100%, specificity 91.7%, positive predictive value 82.5% and negative predictive value 100%. CONCLUSIONS: The Infanib can be used as an appropriate screening tool and validity measurement for early detection of gross motor developmental delay in preterm infants.
LUO Fang,CHEN Zheng,MA Xiao-Lu et al. Infant Neurological International Battery predicts neurological outcomes of preterm infants discharged from the neonatal intensive care unit[J]. CJCP, 2013, 15(1): 5-8.
［3］Mutlu A, Livanelioglu A, Korkmaz A. Assessment of “general movements” in high-risk infants by Prechtl analysis during early intervention period in the first year of life［J］. Turk J Pediatr, 2010, 52(6): 630-637.
［4］van Haastert IC, de Vries LS, Helders PJ, Jongmans MJ. Early gross motor development of preterm infants according to the Alberta Infant Motor Scale［J］. J Pediatr, 2006, 149(5): 617-622.
［5］Ellison PH, Horn JL, Browning CA. Construction of an Infant Neurological International Battery (Infanib) for the assessment of neurological integrity in infancy［J］. Phys Ther, 1985, 65(9): 1326-1331.
［6］Ellison PH.Infant Neurological International Battery has high predictive validity, and test author is a pediatric neurologist［J］. Am J Occup Ther, 1992, 46(9): 855.
［7］Petersen MB, Ellison P, Sharpsteen D.A review of neuromotor tests and the construction of a scored neuromotor examination for four-year-olds［J］. Acta Paediatr Suppl, 1994, 401: 1-16.
［8］Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M, Damiano D, et al. A report: the definition and classification of cerebral palsy April 2006［J］. Dev Med Child Neurol Suppl, 2007, 109: 8-14.
［9］Sung IY, Kang W. Infant Neurological International Battery (INFANIB) as a predictor of neuromotor outcome in risk infants［J］. J Korean Acad Rehabil, 1997, 21(2): 406-413.
［10］Soleimani F, Dadkhah A. Validity and reliability of Infant Neurological International Battery for detection of gross motor developmental delay in Iran［J］.Child Care Health Dev, 2007, 33(3): 262-265.
［11］Shafir T, Angulo-Barroso R, Jing Y, Angelilli ML, Jacobson SW, Lozoff B. Iron deficiency and infant motor development［J］. Early Hum Dev, 2008, 84(7): 479-485.
