Abstract：Several fatal events occurred in Hunan, Guangdong and Sichuan Province in December, 2013. The events were reported by the news media, which followed growing public concern. Currently, more and more vaccines were developed and the immunization was adopted for more objectives. The clinicians, especially pediatricians will face a growing number of clinical problems related to the vaccine. The clinicians should pay attention to learn more knowledge about vaccines. This article describes the definition and classification of "adverse events following immunization" and "serious vaccine product-related reactions", and the signifcance and conclusion of causality assessment following immunization.
YAO Kai-Hu,YANG Yong-Hong. Adverse events following immunization and causality assessment of an adverse event following immunization[J]. CJCP, 2014, 16(1): 1-4.
World Health Organization. Causality assessment of an adverse event following immunization (AEFI). User manual for the WHO revised classification [EB/OL]. [2013-12-26].
Tozzi AE, Asturias EJ, Balakrishnan MR, et al. Assessment of causality of individual adverse events following immunization (AEFI): a WHO tool for global use[J]. Vaccine, 2013, 31(44): 5041-5046.
[7]
Halsey NA, Edwards KM, Dekker CL, et al. Algorithm to assess causality after individual adverse events following immunizations[J]. Vaccine, 2012, 30(39): 5791-5798.
