Epidemiological survey of asthma among children aged 0-14 years in 2010 in urban Zhongshan, China
HUANG Juan, HUANG Dong-Ming, XIAO Xiao-Xiong, FU Si-Mao, LUO Cui-Mei, ZENG Guan, WANG Ye-Hong, WANG Ke-Ming, RUAN Jian, ZHEN Bo-Qiang, LI Min, LI Lan, CUI Bi-Yun, HUANG Gui-Zhen, WANG Gui-Lan, RONG Jia-Yan, HUANG Jian-Mei, XIAO Qiong-Qing, GUO Xiao-Ling
Department of Pediatrics, Zhongshan Bo'ai Hospital, Zhongshan, Guangdong 528400, China
Abstract：Objective To investigate the prevalence, current treatment, and clinical characteristics of asthma, as well as the risk factors for this disease, among children aged 0-14 years in 2010 in urban Zhongshan, China. Methods A total of 10 336 children aged 0-14 years were selected from urban Zhongshan by cluster random sampling. The Third National Childhood Asthma Epidemiological Questionnaire 2010 was used to analyze the prevalence, current treatment, and clinical characteristics of childhood asthma, as well as the risk factors for this disease. Results Asthma was diagnosed in 179 cases (1.73%). The prevalence of asthma in male children was significantly higher than that in female children (2.25% vs 1.16%; P<0.01). Of the 179 patients, severe attacks were common in 104 cases (58.1%), 110 cases (61.5%) had slow onset, 102 cases (57.0%) had gradually relieved conditions, 61 cases (34.1%) suffered from asthma during seasonal transition, and 150 cases (83.8%) developed asthma due to respiratory tract infection. Among all asthmatic children, 71.5% had been treated with inhaled corticosteroids, and 71.5% had been treated with bronchodilator. The multivariate logistic regression analysis showed that a history of penicillin allergy, a family history of allergy, food allergy, eczema, allergic rhinitis, cesarean delivery, family mould, and perinatal passive smoking were independent risk factors for childhood asthma. Conclusions The prevalence of childhood asthma in urban Zhongshan is on a high level, and is associated with gender. The treatment of asthma has been standardized, but still needs further improvement. The onset of asthma attack is influenced by various factors.
HUANG Juan,HUANG Dong-Ming,XIAO Xiao-Xiong et al. Epidemiological survey of asthma among children aged 0-14 years in 2010 in urban Zhongshan, China[J]. CJCP, 2015, 17(2): 149-154.
Masoli M, Fabian D, Holt S, et al. The global burden of asthma: executive summary of the GINA Dissemination Committee report[J]. Allergy, 2004, 59(5): 469-478.
[2]
Valet RS, Gebretsadik T, Carroll KN, et al. High asthma prevelence and increased morbidity among rural children in a Medicaid cohort[J]. Ann Allergy Asthma Immunol, 2011, 106(6): 467-473.
Gerez IF, Lee BW, van Bever HP, et al. Allergies in Asia: difference in prevalence and management compared with western populations[J]. Expert Rrv Clin Immunol, 2010, 6(2): 279-289.
[12]
Benhamou AH, Zamora SA, Eigenmann PA, et al. Correlation between specific immunoglobulin E levels and the severity of seactions in allergic patients[J]. Pediatr Allergy Immunol, 2008, 19(2): 173-179.
[13]
Konstantinou GN, Xepapadaki P, Manousakis E, et al. Assessment of airflow limitation, airway inflammation, and symptomsduring virus-induced wheezing episodes in 4- to 6-year-old children[J]. J Allergy Clin Immunol, 2013, 131(1): 87-93.
[14]
Korppi M. Bacterial infections and pediatric asthma[J]. Immunol Allergy Clin North Am, 2010, 30(4): 565-574.
[15]
Ou CY, Tseng YF, Chiou YH, et al. The role of Mycoplasma pneumoniae in acute exacerbation of asthma in children[J]. Acta Paediatr Taiwan, 2008, 49(1): 14-18.
[16]
Vander Hulst AE, Klip H, Brand PL. Risk of developing asthma in young children with atopic eczema: a systematic review[J]. J Allergy Clin Immunol, 2007, 120: 565-569.
