Correlation between neonatal vitamin D level and maternal vitamin D level
WANG Chen1, GAO Jin-Song2, YU Song-Lin3, QIU Ling3, ZENG Lin4, WANG Dan-Hua1
Department of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Abstract Objective To investigate the correlation between neonatal and maternal vitamin D levels. Methods From June 1 to July 10, 2015, umbilical venous blood samples were collected from 102 full-term single neonates, and venous blood samples were collected from their mothers. Ultra-performance liquid chromatographywith isotope dilution was applied to measure the serum 25(OH)D level. Results Vitamin D insufficiency was found in 39 mothers (38.2%) and 27 neonates (26.5%), and vitamin D deficiency was found in 25 mothers (24.5%) and 66 neonates (64.7%). Neonatal serum 25(OH)D level differed significantly between the groups of mothers with different serum 25(OH)D levels (Pr=0.914, PCI: 0.930-0.994; PConclusions Neonatal vitamin D level is positively correlated with maternal vitamin D level. Maternal vitamin D level can help to predict neonatal vitamin D deficiency.
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