N6-腺苷酸甲基化和铁死亡在儿童变应性鼻炎-哮喘综合征中的研究进展

doi:10.7499/j.issn.1008-8830.2407062

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Abstract Combined allergic rhinitis and asthma syndrome (CARAS) is one of the common chronic airway inflammatory diseases in children. With the development of epigenetics, research on CARAS has gradually extended from protein levels to molecular levels, such as transcription and post-transcriptional regulation. N6-methyladenosine (m6A) methylation and ferroptosis have emerged as promising research hotspots in recent years, playing crucial roles in tumors, growth and development, and allergic diseases. This paper aims to summarize the characteristics of m6A and ferroptosis, along with their roles in the onset and progression of CARAS in children, thereby providing new insights and strategies for the diagnosis and treatment of childhood CARAS.

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	LI Jing-Yi
	LI Yu-Jian
	LAI Sheng-Lin
	KAN Xuan

Key words： Combined allergic rhinitis and asthma syndrome N6-methyladenosine Ferroptosis Allergic rhinitis Allergic asthma Child

Received: 10 July 2024

Corresponding Authors: Email：ashelykx@126.com E-mail: ashelykx@126.com

Cite this article:

LI Jing-Yi,LI Yu-Jian,LAI Sheng-Lin et al. Research progress on N6-methyladenosine and ferroptosis in childhood combined allergic rhinitis and asthma syndrome[J]. CJCP, 2025, 27(2): 242-247.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2407062 OR http://www.zgddek.com/EN/Y2025/V27/I2/242

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