Expression of CD45RA+ and CD45RO+ in PBMCs of Infants with RSV LRTIs
ZHANG Yan-Min, LEI Chun-Lian, CHENG Ge-Sheng, YANG Yu-Cong
Department of Pediatrics, First Hospital of Xi an Jiaotong University, Xi an 710061, China
Abstract OBJECTIVE: To study the expression of CD4+ (helper T lymphocyte), CD45RA+ and CD45RO+ in PBMCs of infants with RSV LRTIs. METHODS: CD4+ and CD45RA+ were detected in 30 patients with RSV LRTIs and CD45RO+ in PBMCs was also assayed except for CD+4 and CD45RO+ in 11 of them with the flow cytometric analysis. Nine healthy children were used as the controls. RESULTS: In RSV infants, CD4+ cells ［(32.74±10.60)%］ decreased and CD45RA+ ［(80.65±10.35)%］ increased compared with the controls ［(40.76±6.82)% and (67.34±7.54)%, respectively］ (P<0.01). CD45RO+ cells also decreased, but not significantly. CONCLUSIONS: There is a disorder of immune function in PBMCs in infants with RSV.
Key words ：
RSV
T help lymphocyte
CD45
Child
Cite this article:
ZHANG Yan-Min,LEI Chun-Lian,CHENG Ge-Sheng et al. Expression of CD45RA+ and CD45RO+ in PBMCs of Infants with RSV LRTIs[J]. 中国当代儿科杂志, 2001, 3(3): 260-261.
ZHANG Yan-Min,LEI Chun-Lian,CHENG Ge-Sheng et al. Expression of CD45RA+ and CD45RO+ in PBMCs of Infants with RSV LRTIs[J]. CJCP, 2001, 3(3): 260-261.
URL:
http://www.zgddek.com/EN/ OR http://www.zgddek.com/EN/Y2001/V3/I3/260
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