Abstract To study the correlation between end-tidal carbon dioxide (PetCO2) and partial pressure of arterial carbon dioxide (PaCO2) in ventilated newborns. Methods Thirty-one ventilated newborn underwent mainstream PetCO2 monitoring; meanwhile, arterial blood gas analysis was performed. The correlation and consistency between PetCO2 and PaCO2 were assessed. Results A total of 85 end-tidal and arterial CO2 pairs were obtained from 31 ventilated newborns. The mean PetCO2 (41±10 mm Hg) was significantly lower than the corresponding mean PaCO2 (46±11 mm Hg) (P2 and PaCO2 (r=0.92, P2 bias was 5.1±4.3 mm Hg (95% limits of consistency, -3.3 to 13.6 mmHg), and 5% (4/85) of the points were beyond the 95%CI. When the oxygenation index (OI) was less than 300 mm Hg (n=48), there was a significant positive correlation between PetCO2 and PaCO2 (r=0.85, P2 bias was 5.9±4.3 mm Hg (95% limits of consistency, -2.6 to 14.5 mm Hg), and 4.2% (2/48) of the points were beyond the 95%CI. When the OI was more than 300 mm Hg (n=37), there was also a significant positive correlation between PetCO2 and PaCO2 (r=0.91, P2 bias was 4.1±4.1 mm Hg (95% limits of consistency, -3.9 to 12.1 mm Hg), and 5% (2/37) of the points were beyond the 95%CI. Conclusions There is a good correlation and consistency between PetCO2 and PaCO2 in ventilated newborns.
FENG Jin-Xing,LIU Xiao-Hong,HUANG Hui-Jun et al. Correlation between end-tidal carbon dioxide and partial pressure of arterial carbon dioxide in ventilated newborns[J]. CJCP, 2014, 16(5): 465-468.
FENG Jin-Xing,LIU Xiao-Hong,HUANG Hui-Jun et al. Correlation between end-tidal carbon dioxide and partial pressure of arterial carbon dioxide in ventilated newborns[J]. CJCP, 2014, 16(5): 465-468.
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