5150例急性下呼吸道感染儿童呼吸道病毒检测结果分析

doi:10.7499/j.issn.1008-8830.2016.01.011

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Abstract Objective To investigate the distribution of respiratory viruses on throat swabs in hospitalized children with acute lower respiratory tract infection (ALRTI). Methods A total of 5 150 children with ALRTI who were admitted to Hebei Children's Hospital between March 2014 and February 2015 were enrolled to investigate the distribution of respiratory viruses in children with ALRTI. Direct immunofluorescence assay was performed for throat swabs from these children to detect influenza virus A (FA), influenza virus B (FB), adenovirus (ADV), respiratory syncytial virus (RSV), and parainfluenza virus types 1, 2, and 3 (PIV-1, PIV-2, and PIV-3). Results Of all the 5 150 throat swabs from hospitalized children, 2 155 (41.84%) had positive virus detection results. RSV had the highest detection rate (1 338 cases/25.98%), followed by PIV-3 (439 cases/8.52%) and FA (166 cases/3.22%), and 29 patients had mixed infection with 2 viruses. With the increasing age, the detection rates of viruses tended to decrease (χ2=279.623; PConclusions The distribution of viruses in children with ALRTI varies with age and season, with RSV prevalence in autumn and winter and PIV-3 prevalence in spring and summer. RSV is the most common viral pathogen that causes ALRTI in hospitalized children.

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	Articles by authors
	LI Quan-Heng
	GAO Wen-Jie
	LI Jin-Ying
	SHI Ling-Ai
	HAO Xiao-Jing
	GE Sheng-Wang
	AN Shu-Hua

Key words： Acute lower respiratory tract infection Respiratory virus Prevalence Child

Received: 20 October 2015

Cite this article:

LI Quan-Heng,GAO Wen-Jie,LI Jin-Ying et al. Detection of respiratory viruses in children with acute lower respiratory tract infection: an analysis of 5 150 children[J]. CJCP, 2016, 18(1): 51-54.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2016.01.011 OR http://www.zgddek.com/EN/Y2016/V18/I1/51

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