Abstract Objective To investigate the distribution of respiratory viruses on throat swabs in hospitalized children with acute lower respiratory tract infection (ALRTI). Methods A total of 5 150 children with ALRTI who were admitted to Hebei Children's Hospital between March 2014 and February 2015 were enrolled to investigate the distribution of respiratory viruses in children with ALRTI. Direct immunofluorescence assay was performed for throat swabs from these children to detect influenza virus A (FA), influenza virus B (FB), adenovirus (ADV), respiratory syncytial virus (RSV), and parainfluenza virus types 1, 2, and 3 (PIV-1, PIV-2, and PIV-3). Results Of all the 5 150 throat swabs from hospitalized children, 2 155 (41.84%) had positive virus detection results. RSV had the highest detection rate (1 338 cases/25.98%), followed by PIV-3 (439 cases/8.52%) and FA (166 cases/3.22%), and 29 patients had mixed infection with 2 viruses. With the increasing age, the detection rates of viruses tended to decrease (χ2=279.623; PConclusions The distribution of viruses in children with ALRTI varies with age and season, with RSV prevalence in autumn and winter and PIV-3 prevalence in spring and summer. RSV is the most common viral pathogen that causes ALRTI in hospitalized children.
LI Quan-Heng,GAO Wen-Jie,LI Jin-Ying et al. Detection of respiratory viruses in children with acute lower respiratory tract infection: an analysis of 5 150 children[J]. CJCP, 2016, 18(1): 51-54.
LI Quan-Heng,GAO Wen-Jie,LI Jin-Ying et al. Detection of respiratory viruses in children with acute lower respiratory tract infection: an analysis of 5 150 children[J]. CJCP, 2016, 18(1): 51-54.
Mehta S, Ngo LH, Dzung DV, et al. Air pollution and admissions for acute lower respiratory infections in young children of Ho Chi Minh City[J]. Air Qual Atmos Health, 2013, 6(1): 167-179.
[11]
Vandini S, Corvaglia L, Alessandroni R, et al. Respiratory syncytial virus infection in infants and correlation with meteorological factors and air pollutants[J]. Italian J Pediatr, 2013, 39(1): 1-6.
Katri B, Eija PS, Hertta O, et al. Adults face increased asthma risk after infant RSV bronchiolitis and reduced respiratory health-related quality of life after RSV pneumonia[J]. Acta Paediatr, 2013, 103(8): 850-855.
