Abstract Objective To study the clinical effect of maternal voice stimulation in alleviating procedural pain in neonates during heel blood collection. Methods A total of 72 neonates who were admitted to the neonate intensive care unit were randomly divided into an intervention group (n=35) and a control group (n=37). Heel blood collection was performed by the routine method in the control group. The intervention group listened to their mothers' voice from 1 minute before heel blood collection to the end of the procedure. Pain score, incidence of crying, and vital signs were recorded before and after heel blood collection. Results Compared with the control group, the heart rate was significantly reduced, the blood oxygen saturation significantly increased, the incidence of crying and the pain score were significantly reduced in the intervention group during the procedure of heel blood collection (P < 0.05). Conclusions Maternal voice stimulation helps to reduce procedural pain and maintain stable vital signs in neonates.
Anand KJ. Effects of perinatal pain and stress[J]. Prog Brain Res, 2000, 122:117-129.
[2]
Cong X, McGrath JM, Cusson RM, et al. Pain assessment and measurement in neonates:an update review[J]. Adv Neonatal Care, 2013, 13(6):379-395.
[3]
Cruz MD, Fernandes AM, Oliveira CR. Epidemiology of painful procedures performed in neonates:a systematic review of observational studies[J]. Eur J Pain, 2016, 20(4):489-498.
[4]
Lago P, Garetti E, Merazzi D, et al. Guidelines for procedural pain in the newborn[J]. Acta Paediatr, 2009, 98(6):932-939.
[5]
Simons SH, van Dijk M, Anand KS, et al. Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates[J]. Arch Pediatr Adolesc Med, 2003, 157(11):1058-1064.
[6]
Grunau RE, Holsti L, Peters JW. Long-term consequences of pain in human neonates[J]. Semin Fetal Neonatal Med, 2006, 11(4):268-275.
[7]
Brummelte S, Grunau RE, Chau V, et al. Procedural pain and brain development in premature newborns[J]. Ann Neurol, 2012, 71(3):385-396.
[8]
Azarmnejad E, Sarhangi F, Javadi M, et al. The effect of mother's voice on arterial blood sampling induced pain in neonates hospitalized in neonate intensive care unit[J]. Glob J Health Sci, 2015, 7(6):198-204.
[9]
Azarmnejad E, Sarhangi F, Javadi M, et al. The effectiveness of familiar auditory stimulus on hospitalized neonates' physiologic responses to procedural pain[J]. Int J Nurs Pract, 2017, 23(3):e12527.
[10]
Haarika V, Soundararajan P, Sundar S, et al. The effectiveness of music and mother's voice on pain reduction during venepuncture in neonates-a randomized control trial[J]. Int J Adv Res, 2017, 5(2):2575-2579.
Provenzi L, Broso S, Montirosso R. Do mothers sound good? A systematic review of the effects of maternal voice exposure on preterm infants' development[J]. Neurosci Biobehav Rev, 2018, 88:42-50.
Stevens BJ, Gibbins S, Yamada J, et al. The premature infant pain profile-revised (PIPP-R):initial validation and feasibility[J]. Clin J Pain, 2014, 30(3):238-243.
[15]
Krueger C. Exposure to maternal voice in preterm infants:a review[J]. Adv Neonatal Care, 2010, 10(1):13-18.
[16]
Rand K, Lahav A. Maternal sounds elicit lower heart rate in preterm newborns in the first month of life[J]. Early Hum Dev, 2014, 90(10):679-683.
[17]
Loewy J, Stewart K, Dassler AM, et al. The effects of music therapy on vital signs, feeding, and sleep in premature infants[J]. Pediatrics, 2013, 131(5):902-918.
[18]
Doheny L, Hurwitz S, Insoft R, et al. Exposure to biological maternal sounds improves cardiorespiratory regulation in extremely preterm infants[J]. J Matern Fetal Neonatal Med, 2012, 25(9):1591-1594.
[19]
Krueger C, Parker L, Chiu S, et al. Maternal voice and shortterm outcomes in preterm infants[J]. Dev Psychobiol, 2010, 52(2):205-212.
[20]
Bozzette M. Healthy preterm infant responses to taped maternal voice[J]. J Perinat Neonatal Nurs, 2008, 22(4):307-316.
[21]
Filippa M, Devouche E, Arioni C, et al. Live maternal speech and singing have beneficial effects on hospitalized preterm infants[J]. Acta Paediatr, 2013, 102(10):1017-1020.
[22]
Schwilling D, Vogeser M, Kirchhoff F, et al. Live music reduces stress levels in very low birth weight infants[J]. Acta Paediatr, 2015, 104(4):360-367.
[23]
Granier-Deferre C, Bassereau S, Ribeiro A, et al. A melodic contour repeatedly experienced by human near-term fetuses elicits a profound cardiac reaction one month after birth[J]. PLoS One, 2011, 6(2):e17304.
[24]
Moon CM, Fifer WP. Evidence of transnatal auditory learning[J]. J Perinatol, 2000, 20(8 Pt 2):S37-S44.
[25]
Committee on Fetus and Newborn and Section on Anesthsthesiology and Pain Medicine. Prevention and management of procedural pain in the neonate:an update[J]. Pediatrics, 2016, 137(2):e20154271.
[26]
Cong X, McGrath JM, Delaney C, et al. Neonatal nurses' perceptions of pain management:survey of the United States and China[J]. Pain Manag Nurs, 2014, 15(4):834-844.
[27]
Dodds E. Neonatal procedural pain:a survey of nursing staff[J]. Paediatr Nurs, 2003, 15(5):18-21.
[28]
Stevens B, Yamada J, Lee GY, et al. Sucrose for analgesia in newborn infants undergoing painful procedures[J]. Cochrane Database Syst Rev, 2013, 1:CD001069.
[29]
Shah V, Ohlsson A. Venepuncture versus heel lance for blood sampling in term neonates[J]. Cochrane Database Syst Rev, 2007, 4:CD001452.
[30]
Chirico G, Cabano R, Villa G, et al. Randomised study showed that recorded maternal voices reduced pain in preterm infants undergoing heel lance procedures in a neonatal intensive care unit[J]. Acta Paediatr, 2017, 106(10):1564-1568.
