青少年起病的成人型糖尿病研究进展

doi:10.7499/j.issn.1008-8830.2408070

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Abstract Maturity-onset diabetes of the young (MODY) is a special type of diabetes characterized by clinical features including early onset of diabetes (before 30 years of age), autosomal dominant inheritance, impaired glucose-induced insulin secretion, and hyperglycemia. So far, 14 types of MODY have been reported, accounting for about 1%-5% of the patients with diabetes. MODY often presents with an insidious onset, and although 14 subtypes have been identified for MODY, it is frequently misdiagnosed as type 1 or type 2 diabetes due to overlapping clinical features and high costs and limitations of genetic testing. This article reviews the clinical features of MODY subtypes in order to improve the accuracy of the diagnosis and treatment of MODY.

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	GENG Hui-Yun
	WANG Zhi-Hua

Key words： Maturity-onset diabetes of the young Gene mutation Clinical manifestation Treatment

Received: 14 August 2024

Corresponding Authors: Wang Z-H,xasetyy@126.com。 E-mail: xasetyy@126.com

Cite this article:

GENG Hui-Yun,WANG Zhi-Hua. Research advances in maturity-onset diabetes of the young[J]. CJCP, 2025, 27(1): 121-126.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2408070 OR http://www.zgddek.com/EN/Y2025/V27/I1/121

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