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2011 Vol.  13 No.  1
Published: 2011-01-15
CLINICAL RESEARCH
EXPERIMENTAL RESEARCH
CLINICAL EXPERIENCE
CASE REPORT
REVIEW
ORIGINAL ARTICLE IN ENGLISH
1 Brigitte LEMYRE, Ling LIU, Gregory Paul MOORE, Sarah Linda LAWRENCE, Nicholas J. BARROWMAN
Do intra-operative fluids influence the need for Post-operative cardiotropic support after a PDA ligation?
OBJECTIVE: To investigate the effect of intra-operative intravenous fluids on post-operative hemodynamic stability. METHODS: We performed a retrospective cohort study of 98 preterm infants who underwent a patent ductus arteriosus (PDA) ligation in one NICU between 2001 and 2007. The primary outcome was the need for cardiotropic support within 24 hrs of ligation. RESULTS: Twenty-seven infants (28%) required post-operative cardiotropic support. The amount of intra-operative fluids varied between 0 and 50.4 mL/kg (median: 10.2 mL/kg). No intra-operative fluid was recorded in 26 patients. Fluids were not associated with the need for post-operative cardiotropic support (P=0.10). Using a multivariate logistic regression model, age at ligation, weight at ligation and pre-operative FiO2 were significant predictors of post-operative cardiotropic support. CONCLUSIONS: Intra-operative fluids do not appear to be associated with the need for post-operative cardiotropic support. A prospective cohort study may help identify modifiable risk factors and improve outcomes in this population.
2011 Vol. 13 (1): 1-7 [Abstract] ( 4529 ) [HTML 1KB] [PDF 859KB] ( 1342 )
CLINICAL RESEARCH
8 WANG Li, ZHU Yan-Ping, LI Ming-Xia
Role of hypoxia-inducible factor-1α endothelin-1 and inducible nitric oxide synthase in the pathogenesis of hypoxia-induced pulmonary hypertension of the newborn
OBJECTIVE: To investigate the roles of hypoxia-inducible factor-1α (HIF-1α), endothelin-1 (ET-1) and inducible nitric oxide synthase (iNOS) in the pathogenesis of hypoxia-induced pulmonary hypertension (HPH) of the newborn. METHODS: Seventy-five term hospitalized neonates with HPH (mild 29 cases, moderate 25 cases, severe 21 cases) and 22 term hospitalized neonates without HPH (control group) were enrolled between June 2006 and November 2009. Serum levels of HIF-1α, iNOS and ET-1 were measured using ELASA 1, 3 and 7 days after birth. RESULTS: Serum concentrations of HIF-1α and ET-1 in the mild, moderate and severe HPH groups were significantly higher than those in the control group (P<0.01) 1 day after birth, and were related to the severity of HPH. The serum iNOS concentrations in the moderate and severe HPH groups were also significantly higher than those in the control group (P<0.01). By 3 days after birth, serum ET-1 concentration in the moderate HPH group and serum concentrations of HIF-1α, ET-1and iNOS in the severe HPH group reminded significantly higher than those in the control group (P<0.05). At 7 days after birth, serum ET-1 concentration in the severe HPH group still remained higher than that in the control group (P<0.05). CONCLUSIONS: Serum levels of HIF-1α, ET-1 and iNOS increase in neonates with HPH, resulting in an imbalance of ET-1 and NO. This may be of importance in the pathogenesis of neonatal HPH.
2011 Vol. 13 (1): 8-11 [Abstract] ( 6106 ) [HTML 1KB] [PDF 908KB] ( 1550 )
12 TONG Mei-Ling, ZHANG Min, CHI Xia, HONG Qin, JIANG Ning-Nan, ZHANG Ting-Xiu, DOU Shu-Juan
Longitudinal study of the physical catch-up growth in 84 preterm appropriate for gestational age infants
OBJECTIVE: To study the growth rhythm of preterm appropriate for gestational age (AGA) infants by investigating their physical catch-up growth characteristics. METHODS: Eighty-four preterm AGA newborns (44 males and 40 females) with gestational ages between 28-36 weeks were enrolled. The weight, length and head circumference were evaluated by Z score according to the criterions of actual and corrected ages. RESULTS: The preterm infants had the catch-up growth in weight, length and head circumference in the first year of life. The growth velocity within the first three months was the highest. The velocity in the weight catch-up was higher than that in the length. CONCLUSIONS: The fastest growing period is the early three month of life in preterm AGA infants. The catch-up growth in weight and length is unbalanced.
2011 Vol. 13 (1): 12-15 [Abstract] ( 5423 ) [HTML 1KB] [PDF 893KB] ( 1706 )
16 FAN Juan, ZHOU Wei, SHU Min, DENG Jian-Jun, ZHU Yu, DENG Si-Yan, GUO Qin, WAN Chao-Min
Nasal carriage of community-acquired methicillin-resistant Staphylococcus aureus in healthy children from Chengdu
OBJECTIVE: To evaluate the prevalence of nasal carriage of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in healthy children from Chengdu. METHODS: Strains of Staphylococcus aureus were isolated from nasal swabs of healthy children from five kindergartens in Chengdu from September, 2005 to December, 2005 and questionnaires were obtained. Antibiotic susceptibility test was performed with agar disk diffusion and Bauer-Kirby on Mueller-Hinton medium method to determine CA-MRSA. mecA and PVL genes were detected with PCR in all of the CA-MRSA isolates. RESULTS: A total of 801 children were enrolled. Overall 147 children (18.4%) were carried with Staphylococcus aureus and 9 (1.1%) were carried with CA-MRSA. All CA-MRSA isolates were positive for mecA gene, and 5 CA-MRSA isolates were positive for PVL gene. Of the 9 CA-MRSA isolates, 6 were multiresistant. CONCLUSIONS: CA-MRSA nasal colonization is present among Chengdu healthy children. The CA-MRSA isolates are multiresistant and parts of CA-MRSA isolates carry PVL gene. The nasal carriage of CA-MRSA in healthy children should be a concerned issue.
2011 Vol. 13 (1): 16-19 [Abstract] ( 5026 ) [HTML 1KB] [PDF 958KB] ( 1568 )
20 WEI Hong-Yan, TAN Bo-Yu, YANG Li-Jun, DENG Nan
Antibiotic resistance of gram-negative Bacillis isolated from children with bronchopneumonia
OBJECTIVE: To study the distribution and antibiotic resistance of gram-negative pathogens isolated from children with bronchopneumonia. METHODS: The distribution and the results of susceptibility tests of 272 strains of gram-negative Bacillis isolated from children with bronchopneumonia during 2009 were analyzed. RESULTS: Among the isolates, the common pathogens were Klebsiella pneumoniae and Escherichia coli. The extended-spectrum β-lactamase (ESBLs) production rate was 52.9%. Compared with the non-ESBLs producing strains, ESBLs-producing strains had a significantly higher drug resistance rate to many antibiotics except amikacin and meropenem (P<0.05). The lowest resistance to ESBLs producing gram negative strains was found for meropenem (0.7%), followed by imipenem, amikacin and cefoperazone/sulbactam. CONCLUSIONS: More attentions should be paid to the high rate of drug-resistance of ESBLs producing strains in children. Antimicrobial therapy should be based on the results of drug resistance surveillance.
2011 Vol. 13 (1): 20-22 [Abstract] ( 5528 ) [HTML 1KB] [PDF 891KB] ( 1760 )
23 LIU Xiu-Zhen, JIANG Lian, WANG Xiao-Mei
Condition of Epstein Barr virus infection in hospitalized children from Wuhan region
OBJECTIVE: To study the condition and clinical characteristics of Epstein Barr virus (EBV) infection in hospitalized children from Wuhan region. METHODS: A total of 14 840 hospitalized children were classified into five age groups: less than 6 months old, 6 months to 1 year old, 1 to 3 years old, 3 to 7 years old and 7 to 15 years old. The antibodies IgM and IgG to EBV capsid antigen (VCA) were detected using ELISA. RESULTS: In the 14 840 hospitalized children, 7 899 were positive for EBV antibodies, with an infection rate of 53.23%. The positive rate of VCA-IgM was 4.05% (601/14 840) and that of VCA-IgG was 49.18% (7 298/14 840). The lowest positive rate of VCA-IgM (0.11%) was found in the group of less than 6 months old and the highest positive rate of VCA-IgG (79.83%) was found in the group of 7 to 15 years old. Of the 601 children with positive VCA-IgM, 429 (71.4%) suffered from respiratory tract infection. CONCLUSIONS: EBV infection is very common in hospitalized children in Wuhan. Respiratory tract infection is a leading disease in children with positive EBV antibodies. The infection rate of EBV in different age groups is different.
2011 Vol. 13 (1): 23-25 [Abstract] ( 4976 ) [HTML 1KB] [PDF 948KB] ( 1299 )
26 DENG Yong-Ji, MA Geng, GUO Yun-Fei, GE Zheng, LU Ru-Gang, WANG Li-Xia, ZHU Hao-Bo, CHEN Chen-Jun
Comparisons of efficacy and safety of tolterodine and oxybutynin in children with idiopathic overactive bladder
OBJECTIVE: To compare the efficacy and safety of tolterodine and oxybutynin in the treatment of idiopathic overactive bladder in children. METHODS: A total of 204 children with idiopathic overactive bladder were randomly divided into three groups (n=68 each): placebo, tolterodine-treated and oxybutynin-treated. The efficacy and safety were evaluated two weeks after treatment. RESULTS: The effective rate was 25% in the placebo group, 89% in the tolterodine-treated group, and 92% in the oxybutynin-treated group. The effective rate in the two treatment groups was significantly higher than that in the placebo group (P<0.05). There was a similar efficacy between the two treatment groups. The incidence of adverse events in the tolterodine-treated group (28%) was significantly lower than that in the oxybutnin-treated group (57%) (P<0.05). CONCLUSIONS: Tolterodine has a similar efficacy to oxybutynin in the treatment of idiopathic overactive bladder in children, with better safety in pharmacotherapy.
2011 Vol. 13 (1): 26-28 [Abstract] ( 6299 ) [HTML 1KB] [PDF 887KB] ( 1978 )
29 SHEN Jie, WANG Fang
Application of laryngeal mask airway anaesthesia combined with sacral canal block in pediatric anaesthesia
OBJECTIVE: To compare the advantages and disadvantages between laryngeal mask airway anaesthesia combined with sacral canal block and single tracheal tube anaesthesia in pediatric surgery. METHODS: Sixty 2-12-year-old children for lower limb or lower abdominal surgery were randomly assigned into two groups: a group that was given laryngeal mask airway anaesthesia combined with sacral canal block and a group was given single tracheal tube anaesthesia (n=30 each). Mean arterial pressure (MAP), SpO2 and heart rate (HR) were recorded before induction of anaesthesia, before and after insertion of laryngeal mask airway (LMA) or tracheal tube (TT) and after removal of LMA or TT. The waking-up time, VAS pain scores and the frequency of mania were recorded after surgery. RESULTS: There were no significant differences in MAP, SpO2 and HR between the combined and single anaesthesia groups before anaesthesia and insertion of LMA or TT, while the MAP and HR in the combined anaesthesia group were significantly lower than those in the single anaesthesia group after insertion and removal of LMA or TT (P<0.05). The VAS pain scores were significantly lower and the waking-up time was significantly shorter in the combined anaesthesia group than those in the single anaesthesia group (P<0.05) after surgery. The frequency of mania after surgery in the combined anaesthesia group was significantly lower than that in the single anaesthesia group (P<0.05). CONCLUSIONS: The hemodynamics is more stable in children during the induction and the waking-time of laryngeal mask anesthesia combined with sacral canal block. The anesthesia may relieve postoperative pain, shorten the waking-up time and decrease the frequency of mania.
2011 Vol. 13 (1): 29-31 [Abstract] ( 4763 ) [HTML 1KB] [PDF 889KB] ( 1368 )
CHILD HEALTH CARE
32 YI Jun-Hui, LI Rong-Rong
Influence of near-work and outdoor activities on myopia progression in school children
OBJECTIVE: To study the influence of near-work and outdoor activities on myopia progression in school children. METHODS: Eighty 7-11-year-old school children with myopia were randomly assigned into an intervention group (n=41) and a control group (n=39). The children in the intervention group did near- and middle-vision activities less than 30 hrs per week and more outdoor activities than 14-15 hrs per week. Myopia progression was observed regularly over 2 years after which ophthalmologists administered questionnaires regarding near-vision work (reading, writing and using computer), middle-vision work (watching TV and extracurricular learning activities), outdoor activities, using nature light, wearing glasses, etc. RESULTS: The annual mean myopia progression (0.38±0.15 D) in the intervention group was significantly lower than that in the control group (0.52±0.19 D; P<0.01). The children in the two groups spent similar amounts of time in near-vision activities, but the children in the intervention group spent less time in middle-vision activities (P<0.01) and more outdoor activities (13.7±2.4 vs 6.2±1.6 hrs/wk; P<0.01). When considering all children in the study, there were 4 factors that significantly correlated with less myopia progression: more outdoor activities, more time spent wearing glasses, more time spent in natural light and less time using a computer. When analyzing the intervention group separately, more outdoor activity was inversely correlated with myopia progression (t=-2.510, P<0.05). Separate analysis of the control group indicated that more time wearing glasses was correlated with less myopia progression (t=-3.115, P<0.05). CONCLUSIONS: Myopia progression in school children may be slowed by more outdoor activities, more time spent in natural light and more time wearing corrective glasses.
2011 Vol. 13 (1): 32-35 [Abstract] ( 9424 ) [HTML 1KB] [PDF 899KB] ( 3075 )
EXPERIMENTAL RESEARCH
36 FU Jian-Hua, YANG Hai-Ping, PAN Li, XUE Xin-Dong, GAO Hong
Effects of TGF-β1 on gene expression of connective tissue growth factor in lung fibroblasts
OBJECTIVE: To study the effects of transforming growth factor-β1 (TGF-β1) on the gene expression of connective tissue growth factor (CTGF) in cultured lung fibroblasts of embryonic rats in vitro. METHODS: Wistar rats of embryonic 19 days were used for primary culture of lung fibroblasts (LFs). The cells in the experimental group were treated by different concentrations (1, 5 or 10 ng/mL) and different durations (12, 24 or 48 hrs) of TGF-β1 to stimulate the LFs. The cells in the control group were cultured in serum-free medium. RT-PCR method was applied to detect CTGF mRNA expression in LFs. RESULTS: Compared with the control group, the levels of CTGF mRNA in LFs in the experimental group increased significantly (P<0.05). CTGF mRNA expression gradually increased with increasing concentration and duration of TGF-β1 treatment (P<0.05). CONCLUSIONS: TGF-β1 can stimulate CTGF gene expression in LFs and increase CTGF gene expression in a dose-and time-dependent manner.
2011 Vol. 13 (1): 36-39 [Abstract] ( 5782 ) [HTML 1KB] [PDF 965KB] ( 1493 )
40 HOU Wei, LIU Hai-Yan, YANG Xu-Dong, ZHOU Jian-Ping, LI Dan, YANG Zhi-Yi, GE Li-Ji
Effect of oxymatrine on the distribution of dendritic cells in lung and spleen tissues of asthmatic mice
OBJECTIVE: To study the effect of oxymatrine (Oxy) on airway inflammation and the distribution of dendritic cells (DC) in lung and spleen tissues of asthmatic mice. METHODS: Fifty BALB/c mice were assigned into five groups (n=10): an asthma model group, a dexamethasone (Dex) treatment group and three Oxy treatment groups (Oxy dose: 20, 40 and 80 mg/kg respectively). The histological changes of lung tissues were observed by hematoxylin and eosin staining. The expression of 33D1 antigen (a marker of DC) in lung and spleen tissues were detected by immunohistochemical staining. RESULTS: The inflammatory reactions of the lung tissues in the Dex or Oxy treatment groups were less severe than those in the asthma model group. 33D1 antigen was remarkably expressed in the lung and spleen tissues of the asthma model group. After Dex treatment, the expression of 33D1 antigen in the lung and spleen tissues decreased significantly (P<0.01). 33D1 antigen expression in the lung tissues was significantly reduced in all of the three Oxy treatment groups in a dose-dependent manner compared with that in the asthma model group (P<0.01). The treatment with Oxy of 40 and 80 mg/kg decreased significantly the 33D1 antigen expression in the spleen tissues (P<0.01). CONCLUSIONS: Oxy can alleviate airway inflammation and reduce the number of DC in lung and spleen tissues of asthma mice, which may be contributed to the mechanism of Oxy for treatment of asthma.
2011 Vol. 13 (1): 40-43 [Abstract] ( 5511 ) [HTML 1KB] [PDF 1168KB] ( 1880 )
44 ZHOU Zhu-Ying, LI Guang-Qian
Effects of W-7 on the expression of GRP78 and neuronal apoptosis in immature rat hippocampus after status convulsion
OBJECTIVE: To investigate the effects of the calmodulin inhibitor W-7 on the expression of the key marker of ERS GRP78 and neuronal apoptosis in the immature rat hippocampus after status convulsion (SC). METHODS: One hundred and seventeen male Sprague-Dawley rats aged 19-21 days were randomly divided into three groups: normal saline control (control), SC with and without W-7 pretreatment. Each of the 3 groups was further subdivided into subgroups sacrificed at 4, 24 and 48 hrs. SC model was prepared using lithium-pilocarpine. GRP78 mRNA expression in the hippocampus was detected by semiquantitative reverse transcription-polymerase chain reaction (RT-PCR). GRP78 protein was ascertained by immunohistochemistry. Neuronal apoptosis was observed with TdT-mediated dUTP nick end labeling (TUNEL). RESULTS: The expression of GRP78 mRNA was significantly increased in the non-pretreated SC group compared with the control group 24 hrs after injection of saline or lithium-pilocarpine (P<0.01), and the expression of GRP78 protein also increased markedly in the seizure group compared with the control group 24 and 48 hrs after the injection (P<0.01). The expression of GRP78 mRNA and protein in the W-7 pretreatment group was significantly higher than both the control and the non-pretreated seizure groups 24 and 48 hrs after injection. The TUNEL positive cells in the hippocampus CA1 in the non-pretreated SC group 24 and 48 hrs after injection (21.0±2.5 and 29.4±2.8, respectively) were increased compared to the control group (7.1±1.4 and 7.3±1.6, respectively; P<0.01). W-7 pretreatment decreased TUNEL positive cells to 15.0±2.5 and 20.0±2.9 at 24 and 48 hrs after injection compared to the non-pretreated seizure group (P<0.01), but the number of TUNEL positive cells in the W-7 pretreatment group remained significantly greater than in the control group (P<0.01). CONCLUSIONS: W-7 may up-regulate the expression of GRP78 and reduce the number of apoptotic neurons, thus provides a neuroprotective effect against brain damage following SC.
2011 Vol. 13 (1): 44-49 [Abstract] ( 5260 ) [HTML 1KB] [PDF 1180KB] ( 1321 )
50 JIANG Chun-Ming, DU Jian-Min, LIU Zhan-Li, CHEN Li-Qiong, FENG Mei, YANG Yi-Hua, WANG Jie-Hua, HUANG Xian-Mei
Effects of recombinant human erythropoietin on serum levels of neuron-specific enolase, S-100β protein and myelin basic protein in rats following status epilepticus
OBJECTIVE: This study examined the effect of recombinant human erythropoietin (r-HuEPO) on the serum levels of neuron-specific enolase (NSE), S-100β protein and myelin basic protein (MBP) in young rats 24 hrs after lithium-pilocarpine-induced status epilepticus (SE) in order to study the potential role of r-HuEPO in epileptic brain damage. METHODS: Forty 19-21-day-old male Sprague-Dawley (SD) rats were randomly divided into four groups (n=10): normal control group, SE, r-HuEPO pretreated-SE and r-HuEPO. SE was induced by lithium-pilocarpine. R-HuEPO (500 IU/kg) was intraperitoneally injected in the r-HuEPO pretreated-SE and r-HuEPO groups 4 hrs before SE. Serum levels of NSE, S-100β and MBP were determined 24 hrs after the SE event. RESULTS: Serum levels of NSE, S-100β and MBP in the SE group increased significantly compared with those in the normal control and the r-HuEPO groups (P＜0.05). The r-HuEPO pretreated-SE group showed significantly decreased serum levels of NSE, S-100β and MBP compared with the SE group (P＜0.05). CONCLUSIONS: r-HuEPO may reduce the expression of NSE, S-100β and MBP and thus might provide an early protective effect against epileptic brain injury.
2011 Vol. 13 (1): 50-52 [Abstract] ( 5211 ) [HTML 1KB] [PDF 902KB] ( 1335 )
53 XIAO Zheng-Xiang, YIN Xiao-Cheng, TAN Yan-Fang, PENG Yan-Hui
Effects of diallyl disulfide on apoptosis of human leukemia K562 cells and expression of Fas, FasL and caspase-8
OBJECTIVE: To study the effects of diallyl disulfide (DADS) on apoptosis of human leukemia K562 cells and possible mechanisms. METHODS: The morphologic changes of leukemia K562 cells after DADS treatment were observed by Hoechst 33258 staining. Cell apoptosis rates after different concentrations and different durations of DADS treatment were determined by flow cytometry. Fas, FasL and caspase-8 mRNA expression was estimated by reverse transcription-polymerase chain reaction (RT-PCR) 48 hrs after DADS treatment. RESULTS: The characteristics of apoptosis in K562 cells induced by DADS were observed. After 24 hrs of DADS treatment, the apoptosis rate of K562 cells increased from (11.60±0.83)% at the concentration of 10 mg/L to (37.94±0.87)% at the concentration of 40 mg/L. The apoptosis rate of K562 cells increased after 40 mg/L DADS with the increasing time from (37.94±0.87)% (24 hrs) to (47.02±0.66)% (72 hrs). Expression of Fas and caspase-8 mRNA increased, while FasL mRNA expression decreased significantly 48 hrs after DADS treatment compared with the control group (P<0.05). CONCLUSIONS: DADS can induce apoptosis of human leukemia K562 cells in a time- and concentration-dependent manner, possibly through increasing Fas and caspase-8 expression and decreasing FasL expression.
2011 Vol. 13 (1): 53-56 [Abstract] ( 4575 ) [HTML 1KB] [PDF 1210KB] ( 1188 )
CLINICAL EXPERIENCE
57 WANG Xiu-Ying, DONG Hai-Yun, XU Yi, LIU Dong-Hai
Clinical features and follow-up analysis of 88 cases of incomplete Kawasaki disease
No abstract available
2011 Vol. 13 (1): 57-59 [Abstract] ( 4200 ) [HTML 1KB] [PDF 888KB] ( 1743 )
60 CHENG Sheng-Quan, LIU Jian-Ping, LIU Li-Wen, DENG Yue-Lin, SUN Li-Jun, NIU Yong-Chun
Long term follow-up study on Kawasaki disease complicated by coronary arterial aneurysm by coronary arterial aneurysm by coronary angiography ang echocardiography in children
No abstract available
2011 Vol. 13 (1): 60-62 [Abstract] ( 4107 ) [HTML 1KB] [PDF 908KB] ( 2459 )
63 LI Dan, LI Xiao-Qing, WANG Zhi-Hua
Clinical analysis of 110 cases of childhood influenza A (H1N1)
No abstract available
2011 Vol. 13 (1): 63-64 [Abstract] ( 3512 ) [HTML 1KB] [PDF 876KB] ( 1057 )
65 LIU Yan, ZHANG Bi-Li, WANG Wen-Hong, FAN Shu-Ying
Pathogens and antimicrobial resistance in children with urinary tract infection
No abstract available
2011 Vol. 13 (1): 65-66 [Abstract] ( 4113 ) [HTML 1KB] [PDF 927KB] ( 1472 )
CASE REPORT
67 HU Ying-Hui, YIN Ju, WU Zhu-Li, PENG Yun, JIANG Zai-Fang
A case report of allergic bronchopulmonary aspergillosis
No abstract available
2011 Vol. 13 (1): 67-68 [Abstract] ( 3767 ) [HTML 1KB] [PDF 898KB] ( 1233 )
69 CHEN Yan, WU Jin-Zhun, CHEN Ling, YANG Xiao-Jing, BAI Hai-Tao
Malignant hyperthermia after the operation under general anesthesia: a case report
No abstract available
2011 Vol. 13 (1): 69-70 [Abstract] ( 4035 ) [HTML 1KB] [PDF 875KB] ( 1228 )
71 ZHANG Guo-Qing, BU Jun, BEI Fei, SUN Jian-Hua
A case report of MN incompatibility hemolytic disease
No abstract available
2011 Vol. 13 (1): 71-71 [Abstract] ( 3754 ) [HTML 1KB] [PDF 861KB] ( 1565 )
REVIEW
72 NING Ning, GUO You-Min, YANG Jian
Neurological assessment of neonatal brain development: a review on methods
No abstract available
2011 Vol. 13 (1): 72-76 [Abstract] ( 5352 ) [HTML 1KB] [PDF 915KB] ( 2375 )
77 LIU Li-Li, ZHOU Cong-Le, HOU Xin-Lin
Research progress on neonatal refractory seizures
No abstract available
2011 Vol. 13 (1): 77-81 [Abstract] ( 5510 ) [HTML 1KB] [PDF 896KB] ( 1633 )
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