Levels of serum epidermal growth factor in premature infants
MAO Zhi-Qin, LI Jun, SUN Mei, HU Guo-Bin, ZHANG Hui
Department of Pediatrics, Second Affiliated Hospital of China Medical University, Shenyang 110004, China
Abstract Objective To evaluate the levels and clinical significance of serum epidermal growth (EGF) in premature infants.Methods Serum EGF concentrations of 10 full-term and 35 premature infants were measured by radio-immunoassay (RIA ) within 24hrs after birth.Results The serum EGF concentrations in premature infants born between 35 and 37 weeks of gestation(0.617±0.22 μg/L)and those born between 28 and 34 weeks of gestation(0.540±0.31 μg/L)were significantly lower than those in full-term infants(0.723±0.18 μg/L)( P<0.01). The asphyxiated premature infants showed a much lower EGF level(0.446±0.24 μg/L) compared with the full-term infants. The EGF concentration of the premature infants with necrotizing enterocolitis was not significantly different from that of the full-term infants. Conclusions The serum EGF concentration is associated with the gestational age. Asphyxia may result in a decreased EGF level.
Key words ：
Epidermal growth factor
Necrotizing enterocolitis
Asphxia
Infant, premature
Cite this article:
MAO Zhi-Qin,LI Jun,SUN Mei et al. Levels of serum epidermal growth factor in premature infants[J]. 中国当代儿科杂志, 2005, 7(3): 243-244.
MAO Zhi-Qin,LI Jun,SUN Mei et al. Levels of serum epidermal growth factor in premature infants[J]. CJCP, 2005, 7(3): 243-244.
URL:
http://www.zgddek.com/EN/ OR http://www.zgddek.com/EN/Y2005/V7/I3/243
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