Abstract Objective To analyze the clinical data of very low birth weight infants (VLBWIs) and extremely low birth weight infants (ELBWIs) (birth weight ≤1 200 g) and to provide prewarning indicators for prognostic evaluation and clinical intervention. Methods A retrospective analysis was performed on the clinical data of 108 VLBWIs and ELBWIs to investigate the maternal history of diseases during pregnancy, neonatal birth status, the process of diagnosis and treatment, and prognosis. Unconditional logistic regression analysis was used to determine prognostic factors. Results Of the 108 preterm infants, 15 had a birth weight of Conclusions The mortality in VLBWIs and ELBWIs is relatively high, and the prognostic factors vary between preterm infants of different ages. Clinicians should discuss management options for the infants on the basis of these findings to increase the survival of preterm infants.
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Cite this article:
WANG Lian,LI Juan,MAO Jian et al. Prognostic factors in very low birth weight infants and extremely low birth weight infants[J]. CJCP, 2014, 16(6): 601-605.
WANG Lian,LI Juan,MAO Jian et al. Prognostic factors in very low birth weight infants and extremely low birth weight infants[J]. CJCP, 2014, 16(6): 601-605.
Navaei F, Aliabady B, Moghtaderi J, et al. Early outcome of preterm infants with birth weight of 1500 g or less and gestational age of 30 weeks or less in Isfahan city, Iran[J].World J Pediatr,2010, 6(3): 228-232.
Iijima S, Arai H, Ozawa Y, et al.Clinical patterns in extremely preterm (22 to 24 weeks of gestation) infants in relation to survival time and prognosis[J].Am J Perinatol, 2009, 26(6): 399-406.
[7]
Sritipsukho S, Suarod T, Sritipsukho P. Survival and outcome of very low birth weight infants born in a university hospital with level II NICU[J].J Med Assoc Thai, 2007, 90(7): 1323-1329.
[8]
Mally PV, Bailey S, Hendricks-Munoz KD. Clinical issues in the management of late preterm infants[J].Curr Probl Pediatr Adolesc Health Care, 2010, 40(9): 218-233.
[9]
Wang Y, Tanbo T, Ellingsen L, et al. Effect of pregestational maternal, obstetric and perinatal factors on neonatal outcome in extreme prematurity[J].Arch Gynecol Obstet, 2011, 284(6): 1381- 1387.
[10]
Corchia C, Ferrante P, Da Frè M, et al. Cause-specific mortality of very preterm infants and antenatal events[J].J Pediatr, 2013, 162(6): 1125-1132.
[11]
Gotsch F, Romero R, Kusanovic JP, et al. The fetal inflammatory response syndrome[J].Clin Obstet Gynecol, 2007, 50(3): 652-683.
[12]
Moyo SR, Hagerstrand I, Nystrom L, et al. Stillbirths and intrauterine infection, histologic chorioamnionitis and microbiological findings[J].Int J Gynaecol Obstet, 1996, 54(2): 115-123.
[13]
Cruz Martinez M, Redondo Aguilar R, Cano Aguilar A, et al. Analysis of perinatal mortality in newborn infants with a birth weight of less than 1000 grams in Hospital San Cecilio in Granada (Spain) over the 1991-2010 period[J].Arch Argent Pediatr, 2013, 111(1): 45-52.
[14]
Crowther CA, McKinlay CJ, Middleton P, et al. Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes[J].Cochrane Database Syst Rev, 2011, (6): CD003935.
[15]
Blumenfeld YJ, Lee HC, Gould JB, et al. The effect of preterm premature rupture of membranes on neonatal mortality rates[J].Obst Gynecol, 2010, 116(6): 1381-1386.
[16]
Easterling TR, Benedetti TJ, Schmucker BC, et al. Maternal hemodynamics in normal and preeclamptic pregnancies: a longitudinal study[J].Obst Gynecol, 1990, 76(6): 1061-1069.
[17]
Hornik CP, Fort P, Clark RH, et al. Early and late onset sepsis in very-low-birth-weight infants from a large group of neonatal intensive care units[J].Early Hum Dev, 2012, 88(2): S69-S74.
[18]
Lim WH, Lien R, Huang YC, et al. Prevalence and pathogen distribution of neonatal sepsis among very-low-birth-weight infants[J].Pediatr Neonatol, 2012, 53(4): 228-234.
[19]
Montagna MT, Lovero G, De Giglio O, et al. Invasive fungal infections in neonatal intensive care units of Southern Italy: a multicentre regional active surveillance (AURORA project)[J].J Prev Med Hyg, 2010, 51(3): 125-130.
