早产儿侵袭性真菌感染药物预防策略的研究进展

doi:10.7499/j.issn.1008-8830.2204158

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Abstract There is a relatively high incidence rate of invasive fungal infection (IFI) in preterm infants admitted to the neonatal intensive care unit (NICU), and early diagnosis of IFI is difficult in clinical practice. The patients developing IFI tend to have severe conditions, a long course of treatment, high hospital costs, high mortality, and poor prognosis, and therefore, the prevention of IFI is of particular importance. At present, fluconazole is often used as the first-line drug for the prevention of IFI in preterm infants, but no consensus has been reached on the specific dose and course of treatment, and there are still controversies over the targeted population and prophylactic effect. This article reviews the recent research on the pharmacological prevention strategies for IFI in preterm infants in the NICU, so as to provide a reference for clinicians.

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	HUANG Fang-Jun
	XIONG Tao
	TANG Jun

Key words： Invasive fungal infection Fluconazole Prophylaxis Preterm infant Very low birth weight infant Extremely low birth weight infant

Received: 25 April 2022

Corresponding Authors: Tang J, Email: tj1234753@sina.com E-mail: tj1234753@sina.com

Cite this article:

HUANG Fang-Jun,XIONG Tao,TANG Jun. Recent research on pharmacological prevention strategies for invasive fungal infection in preterm infants[J]. CJCP, 2022, 24(10): 1171-1177.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2204158 OR http://www.zgddek.com/EN/Y2022/V24/I10/1171

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