Comparative analysis of risk factors for preterm and small-for-gestational-age births

ZHONG Xin-Qi; CUI Qi-Liang

doi:10.7499/j.issn.1008-8830.2014.12.003

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Chinese Journal of Contemporary Pediatrics ›› 2014, Vol. 16 ›› Issue (12) : 1202-1205. DOI: 10.7499/j.issn.1008-8830.2014.12.003

CLINICAL RESEARCH

Comparative analysis of risk factors for preterm and small-for-gestational-age births

ZHONG Xin-Qi, CUI Qi-Liang

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Abstract

Objective To compare the risk factors between preterm and small-for-gestational-age (SGA) births. Methods A total of 1 270 newborns who had no obstetric risk factors or maternal diseases were enrolled in this study. Their mothers' stature, body weight, passive smoking, and history of abnormal pregnancy were investigated using the self-designed questionnaire. The infants were divided into four groups: preterm, appropriate-for-gestational-age (AGA), SGA, and term infants. Multivariate logistic regression analysis was performed to compare the risk factors between preterm and SGA births. Results A weight gain less than 9 kg during pregnancy increased the risks of preterm (OR=1.63, 95% CI: 1.12-2.07) and SGA (OR=1.92, 95% CI: 1.56-2.58). The histories of abortion (OR=1.46, 95% CI: 1.09-1.93) and preterm birth (OR=2.63, 95% CI: 1.81-3.92) were independent risk factors for preterm births, while low pre-pregnancy body mass index (<18.5) (OR=2.16, 95% CI: 1.53-3.16), short stature (<1.55 m) (OR=2.46, 95% CI: 1.78-3.48), and passive smoking (OR=2.24, 95% CI: 1.65-2.98) were independent risk factors for SGA births. Conclusions Due to different risk factors between preterm and SGA births, specific preventive measures should be taken pertinently to reduce the incidence of the two bad pregnancy outcomes.

Key words

Risk factor / Small for gestational age infant / Preterm infant

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ZHONG Xin-Qi, CUI Qi-Liang. Comparative analysis of risk factors for preterm and small-for-gestational-age births[J]. Chinese Journal of Contemporary Pediatrics. 2014, 16(12): 1202-1205 https://doi.org/10.7499/j.issn.1008-8830.2014.12.003

References

[1] 王卫平. 儿科学[M]. 第8版. 北京: 人民卫生出版社, 2013: 93-94.
[2] Anum EA, Springel EH, Shriver MD, eT al. GeneTic conTribuTions To dispariTies in preTerm birTh[J]. PediaTr Res, 2009, 65(1): 1-9.
[3] 徐蓉, 郝加虎, 陶芳标, 等. 10407名单胎活产儿小于胎龄儿发生率及其影响因素的队列研究[J]. 中国妇幼保健, 2012, 27(4): 560-565.
[4] 中国肥胖工作组数据汇总分析协作组. 我国成年体重指数和腰围对相关疾病危险因素异常的预测价值:适宜体重指数和腰围切点的研究[J]. 中华流行病学, 2002, 23(1): 5-10.
[5] 韩京秀, 甘德坤, 翟桂荣, 等. 孕期不同阶段被动吸烟对足月产小于胎龄儿影响的病例-对照研究[J]. 卫生研究, 2006, 35(6): 788-790.
[6] 吴洁, 毛萌. 小于胎龄儿与胰岛素抵抗的研究进展[J]. 实用儿科临床杂志, 2006, 21(2): 117-119.
[7] Hales CN, Barker DJ, Clark PM, eT al. FeTal and infanT growTh and impaired glucose Tolerance aT age 64[J]. BMJ, 1991, 303(6809): 1019-1022.
[8] Barker DJ, Hales CN, Fall CH, eT al. Type 2 (non-insulin-dependenT) diabeTes melliTus, hyperTension and hyperlipidaemia (syndrome X): relaTion To reduced feTal growTh[J]. DiabeTologia, 1993, 36(1): 62-67.
[9] Campbell J, Torres S, Ryan J, eT al. Physical and nonphysical parTner abuse and oTher risk facTors for low birTh weighT among full Term and preTerm babies: a mulTieThnic case conTrol sTudy[J]. Am J Epidemiol, 1999, 150(7): 714-726.
[10] Lundsberg LS, Bracken MB, SafTlas AF. Low-To-moderaTe gesTaTional alcohol use and inTrauTerine growTh reTardaTion, low birThweighT, and preTerm delivery[J]. Ann Epidemiol, 1997, 7(7):498-508.
[11] RuwanpaThirana T, Fernando DN. Risk facTors for 'small for gesTaTional age babies'[J]. Indian J PediaTr, 2014, 81(10): 1000-1004.
[12] WaTanabe H, Inoue K, Doi M, eT al. Risk facTors for Term small for gesTaTional age infanTs in women wiTh low prepregnancy body mass index [J]. J ObsTeT Gynaecol Res, 2010, 36 ( 3) : 506-512.
[13] 卞义华, 马凤英. 小于胎龄儿发生的危险因素及其防治策略[J]. 中国妇幼保健, 2013, 28(16): 2647-2649
[14] 甘德坤, 焦力, 朴文花, 等. 环境香烟烟雾对非吸烟人群健康影响研究进展[J]. 环境与健康杂志, 2000, 17(2): 125-128.
[15] PapasTefanou I, Souka AP, Pilalis A, eT al. FirsT TrimesTer predicTion of small-and large-for-gesTaTion neonaTes by an inTegraTed model incorporaTing ulTrasound parameTers, biochemical indices and maTernal characTerisTics[J]. AcTa ObsTeT Gynecol Scand, 2012, 91(1): 104-111.
[16] BickersTaff M, Beckmann M, Gibbons K, eT al. RecenT cessaTion of smoking and iTs effecT on pregnancy ouTcomes[J]. AusT N Z J ObsTeT Gynaecol, 2012, 52(1): 54-58.
[17] Abel EA. Smoking during pregnancy: a review of effecfs on growTh and developmenT of offspring[J]. Hum Biol, 1980, 52(4): 593-625.
[18] Kiine J, STein Z, Susser M. ConcepTion To birTh: epidemiology of prenaTal developmenT[M]. New York: Oxford UniversiTy Press, 1989.